Analysis of stroke after TEVAR involving the aortic arch

Eur J Vasc Endovasc Surg. 2012 Mar;43(3):269-75. doi: 10.1016/j.ejvs.2011.12.009. Epub 2012 Jan 10.

Abstract

Objective: To analyse the incidence of stroke after thoracic endovascular aortic repair (TEVAR) for aortic arch disease.

Methods: In the last decade, 393 patients received TEVAR at our Institution; in 143 cases the aortic arch was involved (32 zones '0', 35 zones '1' and 76 zone '2'). The left subclavian artery (LSA) was revascularised selectively in 75 cases; the proximal LSA was ligated or occluded with a plug in 55 cases before endograft (EG) deployment.

Results: Initial clinical success, perioperative mortality, spinal cord ischaemia and stroke in TEVAR patients with or without arch involvement were, respectively, 86.7% vs. 94.4%, 4.2% vs. 2.4%, 2.1% vs. 3.6% and 2.8% vs. 1.2%. The stroke rate was 9.4% (P < 0.02) in 'zone 0', 0% in 'zone 1' and 1.3% in 'zone 2' with scans showing severe atheroma and/or thrombus in all cases. Stroke was observed in patients with 2.6% or without 2.9% LSA revascularisation; however, it was never observed in patients in whom the LSA was occluded before EG deployment and in 4.5% of patients in whom it was patent at the time of EG deployment.

Conclusions: Stroke after TEVAR is not infrequent especially when the arch is involved. Careful patient selection together with a strategy to reduce embolisation such as occlusion of supra-aortic trunks before EG deployment may play a beneficial role.

MeSH terms

  • Adult
  • Aged
  • Aorta, Thoracic / surgery*
  • Aortic Diseases / epidemiology*
  • Aortic Diseases / surgery*
  • Blood Vessel Prosthesis
  • Blood Vessel Prosthesis Implantation
  • Causality
  • Comorbidity
  • Endovascular Procedures / adverse effects*
  • Female
  • Follow-Up Studies
  • Humans
  • Incidence
  • Length of Stay
  • Male
  • Middle Aged
  • Postoperative Complications / classification
  • Postoperative Complications / epidemiology
  • Postoperative Complications / etiology
  • Prospective Studies
  • Prosthesis Design
  • Risk Factors
  • Spinal Cord Ischemia / epidemiology
  • Spinal Cord Ischemia / etiology
  • Stents
  • Stroke / epidemiology*
  • Treatment Outcome