[PDF][PDF] Phosphorylation of NEUROG3 links endocrine differentiation to the cell cycle in pancreatic progenitors

NAJ Krentz, D van Hoof, Z Li, A Watanabe, M Tang… - Developmental cell, 2017 - cell.com
During pancreatic development, proliferating pancreatic progenitors activate the proendocrine
transcription factor neurogenin 3 (NEUROG3), exit the cell cycle, and differentiate into …

[PDF][PDF] Integrin-linked kinase mediates therapeutic resistance of quiescent CML stem cells to tyrosine kinase inhibitors

…, N Nakamichi, M Chen, SC Chafe, A Watanabe… - Cell Stem Cell, 2020 - cell.com
Patients with chronic myeloid leukemia (CML) often require lifelong therapy with ABL1 tyrosine
kinase inhibitors (TKIs) due to a persisting TKI-resistant population of leukemic stem cells …

Malignant tumor is the greatest risk factor for pulmonary embolism in hospitalized patients: a single-center study

K Fujieda, A Nozue, A Watanabe, K Shi, H Itagaki… - Thrombosis journal, 2021 - Springer
Background This study aimed to investigate the background of patients who presented with
pulmonary embolism (PE) on contrast-enhanced chest computed tomography (CT) and to …

An Evolutionarily Primitive and Distinct Auxin Metabolism in the Lycophyte Selaginella moellendorffii

S Kaneko, SD Cook, Y Aoi, A Watanabe… - Plant and Cell …, 2020 - academic.oup.com
Auxin is a key regulator of plant growth and development. Indole-3-acetic acid (IAA), a plant
auxin, is mainly produced from tryptophan via indole-3-pyruvate (IPA) in both bryophytes …

Synoptic operative reporting in cancer surgery: A scoping review

A Watanabe, K Nabata, SM Wiseman - The American Journal of Surgery, 2023 - Elsevier
Background Narrative operative reports (NOR) are important for cancer management but
often lack key information. This review investigated the efficacy of synoptic operative reports (…

Quality indicators for thyroid cancer care: What should surgeons know?

A Watanabe, SM Wiseman - … Journal of Surgery, 2023 - americanjournalofsurgery.com
Most individuals diagnosed with thyroid cancer (TC) have differentiated thyroid carcinoma (DTC)(97%)
and a generally excellent prognosis. However, up to 20% of DTC patients may …

Intraoperative frozen section analysis of margin status as a quality indicator in gastric cancer surgery

A Watanabe, H Adamson, H Lim… - Journal of Surgical …, 2023 - Wiley Online Library
Introduction Positive pathologic margins following gastric cancer (GC) resection carries a poor
prognosis. We evaluated intraoperative frozen section (IFS) analysis of resection margins (…

Impact of grade on workup of rectal neuroendocrine tumors: a retrospective cohort study: Grade impact on workup of rectal NETs

A Watanabe, S Rai, L Yip, CJ Brown, JM Loree… - World Journal of …, 2024 - Springer
Background Rectal neuroendocrine tumors (RNETs) are often discovered on screening
colonoscopy. Indications for staging and definitive resection are inconsistent in current …

Risk of lymph node metastasis in early gastric cancer for a Western population

A Watanabe, GJ McKendry, L Yip… - Journal of Surgical …, 2023 - Wiley Online Library
Introduction Endoscopic resection (ER) of early gastric cancer (EGC) is increasingly used in
Eastern countries due to their low rates of lymph node metastasis (LNM); however, there is a …

A new era in surgical research: the evolving role of artificial intelligence

A Watanabe, SM Wiseman - … Journal of Surgery, 2023 - americanjournalofsurgery.com
Conclusion In this brief overview, we highlighted some key capabilities and limitations of
using an AI tool for surgical research. AI technology can improve the efficiency of surgical …