Hansson et al, 1982 (25) | PNR | 32 | Lymph node, cutaneous metastases | III, IV | Fresh and FNAC | DNA ploidy related to overall survival (NS). S-phase fraction* < 10%, better survival after diagnosis of metastases |
Sondergaard et al, 1983 (19) | PNR | 53 | Primary, metastases, nevi | I, II, III, IV | Fresh | DNA ploidy related to overall survival (NS) |
von Roenn et al, 1986 (20) | R | 87 | Primary, nevi | I | Paraffin | DNA ploidy related to disease-free survival (NS) |
Zaloudik et al, 1988 (28) | R | 50 | Primary (nodular) | I | Paraffin | DNA ploidy, no prognostic value |
Kheir et al, 1988 (17) | R | 177 | Primary | I | Paraffin | DNA ploidy* related to overall survival and disease-free survival |
Lindholm et al, 1990 (16) | R | 50 | Primary | I | Paraffin | DNA ploidy, no prognostic value |
Muhonen et al, 1991 (27) | R | 95 | Metastases | IV | Paraffin | DNA aneuploidy and low S-phase fraction, better survival with chemotherapy |
Rode et al, 1991 (29) | R | 26 | Primary, metastases | IV | Paraffin | DNA ploidy, no prognostic value |
Karlsson et al, 1993 (26) | R | 82 | Primary | III | Paraffin | DNA ploidy,* S-phase fraction* related to survival after recurrence |
Heaton et al, 1993 (22) | R | 56 | Lymph node | III | Paraffin | DNA ploidy* related to overall survival |
Karlsson et al, 1996 (30) | RR | 127 | Primary, metastases | IV | Paraffin | High S-phase fraction,* related to better response to chemotherapy and better survival |
Present study | R | 33 | Lymph node | III | Paraffin | DNA ploidy related to overall survival (p = 0.06), S-phase not related to overall survival |