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Research
Open Access

Intraoperative measurement of acetabular component position using imageless navigation during revision total hip arthroplasty

Xin Yu Mei, Ali Etemad-Rezaie, Oleg A. Safir, Allan E. Gross and Paul R. Kuzyk
Can J Surg August 01, 2021 64 (4) E442-E448; DOI: https://doi.org/10.1503/cjs.012420
Xin Yu Mei
From the Division of Orthopaedic Surgery, Mount Sinai Hospital, Toronto, Ont.
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Ali Etemad-Rezaie
From the Division of Orthopaedic Surgery, Mount Sinai Hospital, Toronto, Ont.
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Oleg A. Safir
From the Division of Orthopaedic Surgery, Mount Sinai Hospital, Toronto, Ont.
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Allan E. Gross
From the Division of Orthopaedic Surgery, Mount Sinai Hospital, Toronto, Ont.
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Paul R. Kuzyk
From the Division of Orthopaedic Surgery, Mount Sinai Hospital, Toronto, Ont.
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Abstract

Background: Acetabular component malposition is a major cause of dislocation following total hip arthroplasty (THA). Intellijoint HIP is an imageless navigation tool that has been shown to provide accurate intraoperative measurement of cup position during primary THA without substantially increasing operative time. However, its accuracy in revision THA has not been evaluated. This study therefore aims to assess the accuracy of Intellijoint HIP in measuring cup inclination and anteversion in comparison with computed tomography (CT) during revision THA.

Methods: Intellijoint HIP was used to measure the position of the preexisting cup in 53 consecutive patients undergoing revision THA between December 2018 and February 2020. Two authors blinded to the intraoperative navigation measurements also independently measured cup position using preoperative CT according to Murray’s radiographic definitions. Pearson correlation coefficients with 95% confidence intervals (CIs), paired t tests and Bland–Altman plots were used to assess agreement between navigation- and CT-measured cup position. Statistical analysis was performed using GraphPad Prism, with p values less than 0.05 indicating statistical significance.

Results: There was excellent agreement between navigation and CT measurements for both cup inclination (r = 0.89, 95% CI 0.81–0.93) and anteversion (r = 0.93, 95% CI 0.88–0.96), with the mean absolute difference being 5.2º (standard deviation [SD] 4.0º) for inclination and 4.8º (SD 5.4º) for anteversion. The navigation measurement was within 10º of the radiographic measurement in 47 of 53 (88.7%) cases for inclination and 46 of 53 (86.8%) cases for anteversion.

Conclusion: Imageless navigation demonstrated excellent correlation and agreement with CT measurements for both inclination and anteversion over a wide range of acetabular component positions.

Dislocation following total hip arthroplasty (THA) is a common complication associated with substantial morbidity and increased health care expenditures. A 2009 study of more than 50 000 revision THAs found dislocation to be the most common reason for revision following primary THA, accounting for 22.5% of all revisions and 33% of acetabular revisions.1 Although the causes of dislocation are often multifactorial, many authors agree that cup malposition is one of the most important modifiable risk factors for dislocation. Although controversy exists regarding its inability to account for pelvic tilt and spinopelvic mobility,2 the Lewinnek safe zone of 40º plus or minus 10º inclination and 15º plus or minus 10º anteversion remains a widely accepted target for cup position in modern clinical practice.3

Currently, there is no consensus regarding the optimal method to accurately position the acetabular component within a predetermined safe zone. The most commonly used intraoperative aids are manual mechanical alignment guides that attach onto the cup impactor and allow the surgeon to visually assess cup inclination in reference to the floor, and cup anteversion in reference to the patient’s ipsilateral shoulder. However, studies have shown substantial variability in cup position among acetabular components placed using mechanical alignment guides, with a large number of components being outside the Lewinnek safe zone.4,5 Computer-assisted navigation systems have also been developed to assist in acetabular component positioning. Navigation using computed tomography (CT) has been shown to result in more accurate cup positioning, but it is associated with increased operative time and radiation exposure. 6,7 In comparison, imageless navigation uses intraoperatively registered bony landmarks and mounted sensors to provide real-time data on cup position without the need for preoperative CT or intraoperative fluoroscopy. Despite these advantages, imageless navigation has not been widely adopted into routine clinical practice. Potential reasons for the slow adoption include the cost of the associated equipment, the paucity of literature validating the accuracy of this approach and the increased operative time; studies have reported that the operative time for cases using imageless navigation is up to 58 minutes longer than that for non-navigated cases.8

Intellijoint HIP (Intellijoint Surgical) is an imageless navigation tool that has been shown to provide accurate intraoperative measurement of cup position during primary THA,9 while increasing mean operative time by only 2.9 minutes.10 However, its accuracy in revision THA has not been evaluated. This study therefore aims to assess the accuracy of Intellijoint HIP in measuring cup inclination and anteversion during revision THA, as determined by the level of agreement between intraoperative navigation measurements and radiographic measurements derived from preoperative CT.

Methods

Following approval of the study by the Mount Sinai Hospital Research Ethics Board (project 19-0184-C), Intellijoint HIP was used to intraoperatively measure the inclination and anteversion of the preexisting acetabular component in a prospective cohort of 53 consecutive patients who underwent revision THA between December 2018 and February 2020 at Mount Sinai Hospital in Toronto, Ontario. Preoperative CT was performed in all patients as part of the preoperative planning process. All procedures were performed in the lateral decubitus position by a single surgeon using standard positioning instruments and retractors. The position of the preexisting cup was measured before extensive scar tissue débridement and manual stressing of the in situ acetabular component.

Imageless navigation tool

The IntelliJoint HIP navigation tool has been described in detail in previous studies.11 In short, the navigation tool consists of a miniature camera, a motion tracker and a computer workstation (Figure 1). The anterior pelvic plane is registered at the beginning of the operation using an alignment rod placed parallel to the patient’s back. The camera is mounted on a pelvic platform that is in turn secured to the ipsilateral iliac crest using 2 threaded pins, creating a rigid couple such that any intraoperative movement of the pelvis will also move the camera. The camera captures the movement and position of the motion tracker, which can be magnetically fixed to the cup impactor to measure cup position, or to the greater trochanter to measure leg length and offset. The positions of in situ components are calculated by intraoperatively marking their borders using a navigated pointer device. Specifically, the navigation tool measures radiographic inclination and radiographic anteversion according to Murray’s definitions.12 All data are then transferred to and displayed in real time on the laptop workstation.

Fig. 1
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Fig. 1

Intraoperative photo of the navigation tool in use, demonstrating the positions of the mounted tracker (A), camera (B) and laptop workstation (C).

Radiographic analysis

Two authors (X.Y.M., A.E.-R.) blinded to the intraoperative navigation measurements independently reviewed preoperative CT scans to measure the radiographic inclination (RI) and operative anteversion (OA) of the preexisting acetabular component according to Murray’s definitions. RI was measured in the coronal plane as the angle between a line drawn parallel to the ischial tuberosities and a line connecting the most superior and the most inferior rims of the cup. OA was measured in the sagittal plane as the angle between the longitudinal axis of the patient’s body and a line connecting the most superior and the most inferior rims of the cup. Radiographic anteversion (RA) was then calculated from the measured radiographic inclination and operative anteversion values using the conversion formula from Murray’s original paper: tan(RA) equals cos(RI) multiplied by tan(OA).12 Final CT-measured inclination and anteversion were defined as the mean of the 2 authors’ measurements.

Statistical analysis

Descriptive statistics were used to summarize the baseline demographic characteristics of the study cohort. The Pearson correlation coefficient with 95% confidence intervals (CIs) and paired t test were used to assess the level of agreement between intraoperative and CT measurements of cup inclination and anteversion. Pearson correlation coefficients were characterized as poor (0.00–0.29), fair (0.30–0.59), moderate (0.60–0.79) or very strong (0.80–1.00).13 Bland–Altman plots were constructed to visualize the agreement between intraoperative and CT-measured values. Statistical analysis was performed using GraphPad Prism version 8.4.1 (GraphPad Software). A p value of less than 0.05 was considered statistically significant.

Results

The study cohort consisted of 30 women and 23 men with a mean age of 66.3 years (standard deviation [SD] 12.4 yr, range 40 to 93 yr) and body mass index of 31.0 kg/m2 (SD 6.6 kg/m2, range 20 to 52 kg/m2), respectively. The mean American Society of Anesthesiologists (ASA) classification at the time of surgery was 2.9 (SD 0.5, range 2 to 4). A direct lateral approach to the hip was used in all patients (Table 1). Three patients (5.7%) required a trochanteric slide osteotomy, and 14 patients (26.4%) required an extended trochanteric osteotomy. The most common indication for revision was aseptic loosening (n = 20, 37.7%). The most common procedure performed was isolated acetabular revision (n = 20, 37.7%).

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Table 1

Surgical details

Excellent interrater reliability was observed between the 2 authors performing manual CT measurements for both cup inclination (r = 0.96 [95% CI 0.93 to 0.98], p < 0.001) and anteversion (r = 0.94 [95% CI 0.89 to 0.96], p < 0.001). The mean navigation-recorded inclination and anteversion were 42.1º (SD 14.4º, range −5º to 71º) and 12.2º (SD 17.2º, range −54º to 39º), respectively. The mean CT-measured inclination and anteversion were 41.7º (SD 12.5º, range −8.4º to 70.5º) and 12.7º (SD 19.5º, range −68.1º to 45.8º), respectively. Using CT measurements as the gold standard, only 15 of 53 (28.3%) acetabular components had both inclination and anteversion angles within the Lewinnek safe zone. The mean absolute difference between navigation-recorded and CT-measured component position was 5.2º (SD 4.0º) for cup inclination and 4.8º (SD 5.4º) for cup anteversion. The intraoperative measurement was within 5º of the radiographic measurement in 32 of 53 (60.4%) hips for inclination and in 37 of 53 (69.8%) hips for anteversion. The intraoperative measurement was within 10º of the radiographic measurement in 47 of 53 (88.7%) hips for inclination and 46 of 53 (86.8%) hips for anteversion.

Very strong positive correlations were observed between navigation and CT measurements for both cup inclination (r = 0.89 [95% CI 0.81 to 0.93], p < 0.001) and anteversion (r = 0.93 [95% CI 0.88 to 0.96], p < 0.001). Paired t tests showed no significant difference between navigation and CT measurements for both inclination (mean of differences 0.41º [SD 6.6º], p = 0.66) and anteversion (mean of differences 0.57º [SD 7.2º], p = 0.57). Bland–Altman analysis demonstrated no significant proportional bias for both cup inclination (mean difference 0.40 [SD 6.6]; Figure 2) and anteversion (mean difference 0.57 [SD 7.2]; Figure 3).

Fig. 2
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Fig. 2

Bland–Altman plot showing the difference in cup inclination between navigation and CT measurements against the mean of the 2 measurements. CT = computed tomography; SD = standard deviation.

Fig. 3
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Fig. 3

Bland–Altman plot showing the difference in cup anteversion between navigation and CT measurements against the mean of the 2 measurements. CT = computed tomography; SD = standard deviation.

Discussion

Acetabular component malposition has been shown to increase the risk for postoperative dislocation, component impingement, accelerated bearing wear, and future revision surgery.14,15 Accurate cup placement is especially challenging in revision THA because of distorted anatomy, bone loss secondary to osteolysis and implant removal, as well as higher incidence of soft tissue scarring and contracture. Although many computer-assisted navigation tools have been shown to increase the accuracy of cup placement in primary THA,16,17 to our knowledge only 1 study to date has evaluated the accuracy of navigated cup placement during revision THA.18 We therefore sought to evaluate the accuracy of the imageless navigation tool Intellijoint HIP in measuring cup inclination and anteversion during revision THA, as compared with manual measurements using preoperative CT.

Our study found excellent agreement between navigation-recorded and manual CT measurements for both cup inclination and anteversion over a wide range of cup positions. Furthermore, there was no consistent underestimation or overestimation of cup inclination or anteversion by the navigation system. Our findings add to the existing literature on computer-assisted THA by demonstrating the accuracy of an imageless navigation tool in complex revision THA, as well as its ability to detect malposition of the preexisting acetabular component.

The large proportion of acetabular components found to be outside the Lewinnek safe zone is expected and reflects revision procedures involving aseptic loosening and possible component migration. The large number of patients requiring trochanteric osteotomy also reflects the technical complexity of revision THA. In the only published study to date on navigated revision THA, Chang and colleagues reported on 40 computer-assisted revision THAs using an imageless navigation system (VectorVision, BrainLab). Similar to our study, they found the mean prerevision cup inclination and anteversion to be 40.8º (SD 14.2º, range 14.9º to 81.4º) and 25.8º (SD 15.4º, range 21.8º to 55.3º), respectively, with 23 of 40 (57.5%) cups outside their predetermined safe zone.18 These findings suggest that malposition of the preexisting acetabular component is common in revision THA and may present intraoperative decision-making challenges regarding revision versus retention of a well-fixed acetabular component. Extraction of well-fixed acetabular components with solid bony ingrowth is technically demanding and can increase blood loss and host bone loss, prolong operative time and increase the risk for infection. Navigation tools can facilitate intraoperative decision-making during revision THA as they not only allow identification of malpositioned components, but also help optimize the orientation of new revision components in cases requiring cup revision. This has been demonstrated in 2 case reports where data provided by the navigation tool were integral to intraoperative decision-making regarding cup revision versus retention.19,20

We observed a higher discrepancy between navigation-recorded and CT-measured values in our study (5.2º [SD 4.0º] for inclination and 4.8º [SD 5.4º] for anteversion) in comparison with previous studies involving navigated primary THA. Ybinger and colleagues reported on 37 navigated primary THAs and noted the mean difference between navigation and CT measurements to be 3.5º (SD 4.4º) for inclination and 6.5º (SD 7.3º) for anteversion.21 Similarly, Dorr and colleagues observed a mean difference of 4.4º for inclination and 4.1º for anteversion between navigation and CT measurements in a cohort of 30 navigated primary THAs.22 Possible explanations for the increased discrepancy between navigation and CT measurements seen in our study include the increased body mass index of our patient cohort (mean 31.0 [SD 6.6] kg/m2; range 20 to 52 kg/m2), as well as the distorted anatomy associated with complex revision procedures. Imageless navigation relies on accurate registration of bony landmarks to calculate the anterior pelvic plane for use as a reference for acetabular component position.23 Patients undergoing revision THA often present with distorted anatomy such as substantial pelvic obliquity and pelvic tilt, soft tissue contractures and periprosthetic osteolysis or fractures that can interfere with accurate registration of bony landmarks and lead to intraoperative measurement errors. Furthermore, obesity has been shown to be associated with decreased accuracy of navigated cup placement, probably because of the obscuring of bony landmarks by overlying soft tissue, resulting in measurement error.17,21

Limitations

This study has several limitations. First, we measured and compared the position of the preexisting acetabular component rather than that of the new revision component in cases involving cup revision. Although this eliminated the risk of patient morbidity secondary to navigation error and allowed for testing of navigation accuracy at extreme cup positions outside the Lewinnek safe zone, it limited the ability to extrapolate our results to the insertion of new revision cups. Furthermore, although intraoperative measurements were taken before extensive scar tissue débridement and manual stressing of the preexisting acetabular component, there remained the possibility of cup migration between preoperative CT and intraoperative measurement in cases involving acetabular osteolysis and aseptic loosening, which may have confounded our results. Thus, further studies evaluating the position of newly inserted revision cups are warranted. Second, the maximum clinically acceptable underestimation or overestimation of cup inclination and anteversion by navigation tools in THA remains poorly defined. Although 2 small studies have used 5º as the maximum clinically acceptable margin of error for navigation in hip resurfacing,24,25 no such value has been proposed for THA. Given the distorted anatomy and bone loss routinely encountered in revision THA and the availability of specialized components such as dual mobility cups and constrained liners, we accepted a 10º margin of error. However, we acknowledge that the clinically acceptable margin of error may vary among surgeons, and thus this limits the strength of our conclusions. Finally, we did not report on clinical outcomes but confined our study to radiographic findings.

Conclusion

Imageless navigation demonstrated excellent correlation and agreement with CT measurements for both cup inclination and anteversion over a wide range of acetabular component positions and patient body habitus. However, its accuracy in revision THA may be lower than its accuracy in primary THA. Further study is needed to elucidate the limitations of and specific contraindications for imageless navigation during revision THA and to evaluate whether navigation results in a reduction of adverse events and improved clinical outcomes.

Footnotes

  • Competing interests: A. Gross holds stock and stock options in Intellijoint Surgical. No other competing interests were declared.

  • Contributors: X. Mei, O. Safir, A. Gross and P. Kuzyk designed the study. X. Mei and A. Etemad-Rezaie acquired the data, which X. Mei, A. Etemad-Rezaie and P. Kuzyk analyzed. X. Mei and A. Etemad-Rezaie wrote the article, which all authors critically revised. All authors approved the final version to be published.

  • Accepted October 5, 2020.

This is an Open Access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY-NC-ND 4.0) licence, which permits use, distribution and reproduction in any medium, provided that the original publication is properly cited, the use is noncommercial (i.e., research or educational use), and no modifications or adaptations are made. See: https://creativecommons.org/licenses/by-nc-nd/4.0/

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Canadian Journal of Surgery: 64 (4)
Can J Surg
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1 Jul 2021
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Intraoperative measurement of acetabular component position using imageless navigation during revision total hip arthroplasty
Xin Yu Mei, Ali Etemad-Rezaie, Oleg A. Safir, Allan E. Gross, Paul R. Kuzyk
Can J Surg Aug 2021, 64 (4) E442-E448; DOI: 10.1503/cjs.012420

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Intraoperative measurement of acetabular component position using imageless navigation during revision total hip arthroplasty
Xin Yu Mei, Ali Etemad-Rezaie, Oleg A. Safir, Allan E. Gross, Paul R. Kuzyk
Can J Surg Aug 2021, 64 (4) E442-E448; DOI: 10.1503/cjs.012420
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