PT  - JOURNAL ARTICLE
AU  - Robert S. Bell
AU  - Sevan Hopyan
AU  - Aileen M. Davis
AU  - Rita Kandel
AU  - Allan E. Gross
TI  - Sarcoma of bone–cement membrane: a case report and review of the literature
DP  - 1997 Feb 01
TA  - Canadian Journal of Surgery
PG  - 51--55
VI  - 40
IP  - 1
4099  - http://canjsurg.ca/content/40/1/51.short
4100  - http://canjsurg.ca/content/40/1/51.full
SO  - CAN J SURG1997 Feb 01; 40
AB  - The development of a cancerous tumour at the site of total joint replacement is a rare but virtually always fatal event. The previously unreported scenario of a patient who was found to have a malignant fibrous histiocytoma at the bone–cement membrane after revision for a loose total hip prosthesis is reported. Recent biologic information evaluating the response of mesenchymal cells to metallic debris suggests that the environment surrounding a loosened prosthesis may provide conditions appropriate for the development of a sarcoma.