RT Journal Article
SR Electronic
T1 Sarcoma of bone–cement membrane: a case report and review of the literature
JF Canadian Journal of Surgery
JO CAN J SURG
FD Canadian Medical Association
SP 51
OP 55
VO 40
IS 1
A1 Robert S. Bell
A1 Sevan Hopyan
A1 Aileen M. Davis
A1 Rita Kandel
A1 Allan E. Gross
YR 1997
UL http://canjsurg.ca/content/40/1/51.abstract
AB The development of a cancerous tumour at the site of total joint replacement is a rare but virtually always fatal event. The previously unreported scenario of a patient who was found to have a malignant fibrous histiocytoma at the bone–cement membrane after revision for a loose total hip prosthesis is reported. Recent biologic information evaluating the response of mesenchymal cells to metallic debris suggests that the environment surrounding a loosened prosthesis may provide conditions appropriate for the development of a sarcoma.