PT  - JOURNAL ARTICLE
AU  - George Miller
AU  - Jason Boman
AU  - Ian Shrier
AU  - Philip H. Gordon
TI  - Small-bowel obstruction secondary to malignant disease: an 11-year audit
DP  - 2000 Oct 01
TA  - Canadian Journal of Surgery
PG  - 353--358
VI  - 43
IP  - 5
4099  - http://canjsurg.ca/content/43/5/353.short
4100  - http://canjsurg.ca/content/43/5/353.full
SO  - CAN J SURG2000 Oct 01; 43
AB  - Objective: To determine the efficacy and long-term prognosis for operative versus nonoperative treatment of small-bowel obstruction (SBO) secondary to malignant disease.Design: A chart review.Setting: A university-affiliated teaching hospital.Patients: The medical records of all patients with malignant disease as the established etiology of their obstruction who presented to the Sir Mortimer B. Davis-Jewish General Hospital, Montreal, between 1986 and 1996 were reviewed. There were 32 patients accounting for 74 admissions.Interventions: Selective nonoperative management and exploratory laparotomy, immediate or delayed.Main outcome measures: The value of nonoperative management and need for operation.Results: Colorectal and ovarian neoplasms were the principal primary malignant diseases that led to SBO. The median time between diagnosis of the malignant disease and SBO was 1.1 years. At their initial presentation, 80% of patients were treated by operation, but 47% of these patients had an initial trial of nonoperative treatment. Reobstruction occurred in 57% of patients who were operated on compared with 72% of patients who were not. The median time to reobstruction was 17 months for patients who underwent operation compared with 2.5 months for patients who did not. Also, 71% of patients were alive and symptom free 30 days after discharge from operative treatment compared with 52% after nonoperative treatment. Postoperative morbidity was 67%. Mortality was 13%, and 94% of patients eventually died from complications of their primary disease.Conclusions: SBO secondary to malignant disease usually indicates a grim prognosis. Operative treatment has better outcome than nonoperative management in terms of symptom free interval and reobstruction rates. However, it is marked by high postoperative morbidity. We recommend that, after short trial of nasogastric decompression, patients with obstruction secondary to malignant disease be operated on if clinical factors indicate they they will survive the operation.