RT Journal Article
SR Electronic
T1 High-risk medications in older patients with trauma: a cross-sectional study of risk mitigation
JF Canadian Journal of Surgery
JO CAN J SURG
FD Canadian Medical Association
SP 100
OP 104
DO 10.1503/cjs.017117
VO 62
IS 2
A1 Erica Lester
A1 Mark Dykstra
A1 Chantalle Grant
A1 Vanessa Fawcett
A1 Bonnie Tsang
A1 Sandy Widder
YR 2019
UL http://canjsurg.ca/content/62/2/100.abstract
AB Background: The Beers Criteria for Potentially Inappropriate Medication Use in Older Adults is a framework that can assess the nature of high-risk medication use. The objective of this study was to use the Beers Criteria to assess the prevalence and nature of polypharmacy, the magnitude of medication changes during the hospital stay and the impact of Beers Criteria medications on outcomes in older patients with trauma.Methods: We used the Alberta Trauma Registry to conduct a retrospective review of patients aged 65 years or older with major trauma (Injury Severity Score ≥ 12) who were admitted to a level 1 trauma centre between January 2013 and December 2014. We analyzed changes in medication prescriptions during the hospital stay using descriptive statistics and assessed the association between Beers Criteria medications and relevant outcomes using multivariable regression analysis.Results: There was no significant change in the number of Beers Criteria medications prescribed before and after admission. The adjusted odds ratio for 30-day mortality for each additional Beers Criteria medication prescribed was 2.02 (95% confidence interval [CI] 1.16–3.51) versus 1.24 (95% CI 1.04–1.59) for each additional medication of any type. The corresponding adjusted incidence rate ratios for length of stay were 1.15 (95% CI 1.03–1.30) versus 1.05 (95% CI 1.01–1.10).Conclusion: Beers Criteria medications were not discontinued during trauma admissions. Using the Beers Criteria as a process indicator for quality improvement in trauma care may provide interdisciplinary trauma teams an opportunity to audit patient medications and stop potentially harmful medications in a vulnerable population.