RT Journal Article
SR Electronic
T1 Surgical site infection following abdominal surgery: a prospective cohort study
JF Canadian Journal of Surgery
JO CAN J SURG
FD Canadian Medical Association
SP 111
OP 117
DO 10.1503/cjs.004818
VO 62
IS 2
A1 Aroub Alkaaki
A1 Osman O. Al-Radi
A1 Ahmad Khoja
A1 Anfal Alnawawi
A1 Abrar Alnawawi
A1 Ashraf Maghrabi
A1 Abdulmalik Altaf
A1 Murad Aljiffry
YR 2019
UL http://canjsurg.ca/content/62/2/111.abstract
AB Background: Surgical site infection (SSI) is one of the most common complications of abdominal surgery and is associated with substantial discomfort, morbidity and cost. The goal of this study was to describe the incidence, bacteriology and risk factors associated with SSI in patients undergoing abdominal surgery.Methods: In this prospective cohort study, all patients aged 14 years or more undergoing abdominal surgery between Feb. 1 and July 31, 2016, at a single large academic hospital were included. Patients undergoing vascular, gynecological, urological or plastic procedures were excluded. Patients were followed prospectively for 30 days. Wound assessment was done with the Centers for Disease Control and Prevention definition of SSI. We performed multivariate analysis to identify factors associated with SSI.Results: A total of 337 patients were included. The overall incidence of SSI was 16.3% (55/337); 5 patients (9%) had deep infections, and 25 (45%) had combined superficial and deep infections. The incidence of SSI in open versus laparoscopic operations was 35% versus 4% (p < 0.001). The bacteria most commonly isolated were extended-spectrum β-lactamase-producing Escherichia coli, followed by Enterococcus species. Only 23% of cultured bacteria were sensitive to the prophylactic antibiotic given preoperatively. The independent predictors of SSI were open surgical approach, emergency operation, longed operation duration and male sex.Conclusion: Potentially modifiable independent risk factors for SSI after abdominal surgery including open surgical approach, contaminated wound class and emergency surgery should be addressed systematically. We recommend tailoring the antibiotic prophylactic regimen to target the commonly isolated organisms in patients at higher risk for SSI.