PT  - JOURNAL ARTICLE
AU  - Ning Guo
AU  - Quan B. Zhou
AU  - Ru F. Chen
AU  - Sheng Q. Zou
AU  - Zhi H. Li
AU  - Qing Lin
AU  - Jie Wang
AU  - Ji S. Chen
TI  - Diagnosis and surgical treatment of solid pseudopapillary neoplasm of the pancreas: analysis of 24 cases
AID  - 10.1503/cjs.011810
DP  - 2011 Dec 01
TA  - Canadian Journal of Surgery
PG  - 368--374
VI  - 54
IP  - 6
4099  - http://canjsurg.ca/content/54/6/368.short
4100  - http://canjsurg.ca/content/54/6/368.full
SO  - CAN J SURG2011 Dec 01; 54
AB  - Background: Our aim was to summarize our experience with the diagnosis and surgical treatment of solid pseudopapillary neoplasm (SPN) of the pancreas to provide a reference for the management of this rare condition.Methods: We collected and analyzed retrospective data on the clinical presentation, laboratory investigations, radiologic imaging, pathology and operative details of patients with SPN of the pancreas diagnosed between February 2001 and December 2009.Results: In all, 23 of 24 patients were women, and the mean age of all patients was 31 years. The most common clinical presentation was vague abdominal pain. Abdominal imaging showed solid or solid cystic masses in the pancreas, mostly in the tail or head of the gland. All patients were treated surgically. There were no postoperative deaths. After follow-up ranging from 4 to 109 months (median 68 mo), 20 of 22 patients who underwent curative resection were alive with no evidence of disease recurrence. Of the 2 patients with R1 resections, 1 died 42 months after surgery, whereas the other underwent a second operation and was alive after 36 months’ follow-up.Conclusion: Solid pseudopapillary neoplasm of the pancreas is a relatively indolent tumour. The initial diagnosis of SPN of the pancreas is suggested by radiologic imaging findings but should be considered in the context of clinical and histopathologic characteristics. We advocate for complete surgical resection once SPN is diagnosed.