Patient | Duration of disease, wk | Follow-up; ulcer size, cm3 | ||||||
---|---|---|---|---|---|---|---|---|
0 (baseline) | 1 wk | 4 wk | 8 wk | 12 wk | 16 wk | 20 wk | ||
1 | 32 | 31.2 | 26.2 | 12.6 | 5.5 | Healed | — | — |
2 | 18 | 148.6 | 133.6 | 124.0 | 107.6 | 89.7 | 768.0 | 66.6* |
3 | 84 | 25.8 | 22.5 | 19.7 | 16.5 | 14.0 | 12.6 | 11.3† |
4 | 30 | 47.6 | 40.2 | 22.0 | 9.0 | Healed | — | — |
5 | 32 | 45.0 | 40.4 | 20.5 | 8.8 | Healed | — | — |
6 | 40 | 86.8 | 74.3 | 42.1 | 23.4 | 9.3 | Healed | — |
7 | 80 | 36.0 | 30.2 | 25.5 | 20.2 | 18.4 | 14.0 | 11.5‡ |
8 | 24 | 358.8 | 320.4 | 202.0 | 126.6 | 71.3 | 22.0 | Healed |
9 | 72 | 24.6 | 22.1 | 18.7 | 14.0 | 11.7 | 10.0 | 9.3† |
10 | 42 | 89.0 | 81.2 | 74.4 | 65.0 | 56.0 | 50.3 | 43.9‡ |
11 | 36 | 109.0 | 100.0 | 93.7 | 87.2 | 76.0 | 65.0 | 58.5† |
12 | 24 | 14.0 | 12.0 | 7.2 | 2.9 | Healed | — | — |
13 | 20 | 38.0 | 31.8 | 18.2 | 6.4 | Healed | — | — |
14 | 22 | 37.8 | 32.7 | 18.2 | 6.0 | Healed | — | — |
15 | 36 | 122.2 | 110.0 | 85.4 | 54.0 | 29.6 | 9.0 | Healed |