Incidence of spontaneous adverse events reported during the study period
| Event | Therapy; no. of events | |
|---|---|---|
| CR oxycodone (n = 90) | Standard therapy (n = 97) | |
| Nausea and vomiting | 59 | 75 |
| Somnolence | 38 | 11 |
| Constipation | 30 | 20 |
| Dizziness | 18 | 15 |
| Confusion | 13 | 2 |
| Fever | 10 | 20 |
| Sweating | 8 | 8 |
| Tachycardia | 6 | 3 |
| Insomnia | 4 | 8 |
| Dyspepsia | 4 | 7 |
| Pruritis | 1 | 27 |