Factor | Group; mean ± SEM | ||||
---|---|---|---|---|---|
Sham | Wild type | MBL K/O | C1q K/O | Factor B K/O | |
Gut permeability, units/uL serum I125 activity/90 min of reperfusion | 1.64 ± 0.53 | 6.61 ± 1.75* | 3.32 ± 0.69 | 1.92 ± 0.21 | 2.84 ± 0.35 |
Gut neutrophil sequestration, MPO/mg gut protein | 0.20 ± 0.05 | 0.38 ± 0.04* | 0.27 ± 0.06 | 0.05 ± 0.01 | 0.07 ± 0.01 |
C1q = classical; K/O = knockout; MBL = mannan-binding lectin; MPO = myeloperoxidase; SEM = standard error of the mean.
↵* p < 0.05 v. Sham.