Incidence and associations of papillary thyroid carcinoma bilaterality with patient and cancer characteristics and with MACIS score
| Characteristic | Group; no. (%) | p value | |
|---|---|---|---|
| Bilateral | Unilateral | ||
| Sex | 0.52 | ||
| Female | 55 (67.1) | 90 (74.4) | |
| Male | 27 (32.9) | 31 (25.6) | |
| Age, yr | 0.36 | ||
| < 45 | 31 (37.8) | 59 (48.8) | |
| ≥ 45 | 51 (62.2) | 62 (51.2) | |
| Extrathyroidal extension | 0.78 | ||
| No | 49 (61.2) | 78 (65.0) | |
| Yes | 31 (38.8) | 42 (35.0) | |
| Size, cm | < 0.001 | ||
| ≤ 1 | 22 (26.8) | 0 | |
| > 1 | 60 (73.1) | 121 (100) | |
| Vascular extension | 0.001 | ||
| No | 66 (80.5) | 119 (98.3) | |
| Yes | 16 (19.5) | 2 (1.7) | |
| Multifocal disease | < 0.001 | ||
| No | 0 | 118 (97.5) | |
| Yes | 82 (100) | 3 (2.5) | |
| Lymph node metastases | 0.36 | ||
| No | 46 (56.8) | 82 (67.8) | |
| Yes | 35 (43.2) | 39 (32.2) | |
| Distant metastases | 0.52 | ||
| No | 77 (96.3) | 120 (99.2) | |
| Yes | 3 (3.8) | 1 (0.8) | |
| MACIS score | 0.78 | ||
| < 6 | 65 (82.3) | 92 (76.7) | |
| 6–6.99 | 7 (8.9) | 17 (14.2) | |
| 7–7.99 | 4 (5.1) | 6 (5.0) | |
| > 8 | 3 (3.8) | 5 (4.2) | |
| MACIS score | > 0.99 | ||
| < 7 | 72 (91.1) | 109 (90.8) | |