Demographic and clinical characteristics
| Characteristic | No. (%) of patients* | p value | |
|---|---|---|---|
| Uniportal VATS n = 65 | Multiportal VATS n = 63 | ||
| Age, yr, mean ± SD | 67.6 ± 8.9 | 69.2 ± 7.9 | 0.28 |
| Male sex | 32 (49) | 21 (33) | 0.08 |
| BMI, mean ± SD | 29.0 ± 7.8 | 27.0 ± 4.5 | 0.10 |
| FEV1, L, mean ± SD | 2.0 ± 0.6 | 2.0 ± 0.6 | 0.74 |
| FEV1, % predicted, mean ± SD | 84.2 ± 21.9 | 87.3 ± 19.9 | 0.43 |
| DLCO, % predicted, mean ± SD | 65.6 ± 20.0 | 65.8 ± 19.0 | 0.95 |
| Current smoker | 13 (20.0) | 16 (25.4) | 0.77 |
| Smoking history | 53 (81.5) | 48 (76.1) | 0.52 |
| Average pack years, mean ± SD | 32.2 (±16.5) | 37.9 (17.0) | 0.10 |
| Comorbidities | |||
| Hypertension | 39 (60.0) | 40 (63.5) | 0.72 |
| COPD | 21 (32.3) | 10 (15.9) | 0.04 |
| Diabetes mellitus | 18 (27.7) | 11 (17.5) | 0.21 |
| Dyslipidemia | 14 (21.5) | 7 (11.1) | 0.15 |
| Hypercholesterolemia | 13 (20.0) | 6 (9.5) | 0.14 |
| Coronary artery disease | 11 (16.9) | 5 (7.9) | 0.18 |
| Previous stroke | 3 (4.6) | 5 (7.9) | 0.49 |
| Histologic type | 0.27 | ||
| Adenocarcinoma | 48 (73.8) | 36 (57.1) | |
| Metastatic tumour | 5 (7.7) | 6 (9.5) | |
| Squamous cell carcinoma | 5 (7.7) | 8 (12.7) | |
| Neuroendocrine tumour | 3 (4.6) | 2 (3.2) | |
| Carcinoid tumour | 2 (3.1) | 3 (4.8) | |
| Other | 3 (4.6) | 5 (7.9) | |
| Tumour size, cm, mean ± SD | 2.7 ± 1.5 | 2.8 ± 1.7 | 0.86 |
| Tumour location | 0.11 | ||
| Left upper lobe | 13 (20.0) | 25 (39.7) | |
| Left lower lobe | 16 (24.6) | 7 (11.1) | |
| Right upper lobe | 14 (21.5) | 11 (17.5) | |
| Right middle lobe | 8 (12.3) | 6 (9.5) | |
| Right lower lobe | 14 (21.5) | 13 (20.6) | |
| Cancer stage | 0.70 | ||
| 0 | 1 (1.5) | 0 | |
| IA | 21 (32.3) | 19 (30.2) | |
| IB | 25 (38.5) | 19 (30.2) | |
| IIA | 3 (4.6) | 4 (6.3) | |
| IIB | 3 (4.6) | 2 (3.2) | |
| IIIA | 7 (10.8) | 8 (12.7) | |
| Operative procedure | 0.71 | ||
| Lobectomy | 43 (58.9) | 40 (57.1) | |
| Segmentectomy | 20 (27.4) | 17 (24.3) | |
| Wedge resection | 10 (13.7) | 13 (18.6) | |
BMI = body mass index; COPD = chronic obstructive pulmonary disease; DLCO = diffusing capacity of the lungs for carbon monoxide; FEV1 = forced expiratory volume in 1 second; SD = standard deviation; VATS = video-assisted thoracoscopic surgery.
↵* Unless indicated otherwise.