Table 1

Baseline clinicopathological characteristics of groups A and B*

CharacteristicNo. (%) of patientsp value
Group A
n = 275
Group B
n = 196
Age, yr, mean ± SD52.3 ± 11.652.7 ± 11.40.7
Male sex240 (87.3)171 (87.2)0.99
Preoperative α-fetoprotein level ≥ 400 ng/mL86 (31.3)64 (32.6)0.8
Hepatitis B surface antigen positive241 (87.6)172 (87.8)0.97
Preoperative platelet count, ×109/L, mean ± SD193.2 ± 83.3188.2 ± 67.60.5
Preoperative total bilirubin level, μmol/L, mean ± SD15.2 ± 6.715.8 ± 6.50.3
Preoperative albumin level, g/L, mean ± SD40.5 ± 3.840.8 ± 4.50.6
Preoperative alanine transaminase level ≥ 50 U/L70 (25.4)53 (27.0)0.7
Preoperative γ-glutamyl transpeptidase level ≥ 75 U/L101 (36.7)59 (30.1)0.1
Tumour size, cm, mean ± SD5.9 ± 3.76.2 ± 4.00.4
Multiple lesions29 (10.5)29 (14.8)0.2
Cirrhosis213 (77.4)113 (57.6)< 0.001
Microvascular invasion105 (38.2)74 (37.8)0.9
Tumour differentiation0.97
 Well32 (11.6)24 (12.2)
 Moderate175 (63.6)125 (63.8)
 Low68 (24.7)47 (24.0)
BCLC stage0.1
 048 (17.4)21 (10.7)
 A96 (34.9)69 (35.2)
 B131 (47.6)106 (54.1)
  • BCLC = Barcelona Clinic Liver Cancer; SD = standard deviation.

  • * Group A: postoperative splenic volume increase less than 19.0%; group B: postoperative splenic volume increase 19.0% or greater.

  • Except where noted otherwise.