Characteristics of patients
| Characteristic | Infliximab (group A), n = 11 | Surgery (group B), n = 10 | Infliximab + surgery (group C), n = 14 |
|---|---|---|---|
| Sex, male:female ratio | 4:7 | 3:7 | 6:8 |
| Current regular smoker, no. of patients | 4 | 3 | 6 |
| Median (range) | |||
| Age, yr | 36.3(19–63) | 33.1 (16–58) | 35.3 (18–65) |
| Duration of disease, yr | 8.8(1–14) | 7.9 (0.9–18) | 7.4 (0.8–21) |
| Duration of fistula, mo | 13.8(6–33) | 14.5 (4–29) | 12.1 (5–42) |
| Preoperative PCDAI score | 10.7(7–13) | 11.2 (7–15) | 11.07 (9–16) |
| Disease location, no. of patients | |||
| Small bowel | 2 | 2 | 3 |
| Colon | 4 | 3 | 4 |
| Small bowel and colon | 5 | 5 | 6 |
| Perianal only | 0 | 0 | 1 |
| Previous procedure, no. of patients | |||
| Resection for Crohn disease | 5 | 3 | 0 |
| Perianal surgery | 3 | 2 | 8 |
| Immunomodulator therapy | 11 | 10 | 14 |
| Antibiotics | 11 | 10 | 14 |
| Anti-TNF-α therapy | 2 | 3 | 1 |
| Magnetic resonance imaging | 4 | 3 | 5 |
| Endoscopic ultrasonography | 7 | 7 | 9 |
PCDAI = Perianal Crohn’s Disease Activity Index; TNF = tumour necrosis factor.