Table 4

Perioperative outcomes recorded in matched pairs of younger and older patients who received tranexamic acid

OutcomeNo. (%) of patients*p value
Age < 65 yr
n = 58
Age ≥ 65 yr
n = 58
Hematologic
Preoperative hemoglobin level, mean ± SD; g/L135.58 ± 10.03132.67 ± 11.310.5
Lowest postoperative hemoglobin level, mean ± SD; g/L101.48 ± 10.4199.79 ± 10.430.6
% decrease in hemoglobin level, mean ± SD25.06 ± 6.5024.65 ± 6.270.4
Estimated total blood loss, mean ± SD; mL1281 ± 3821208 ± 4070.3
Packed erythrocytes transfusion0 (0)1 (2)0.2
Total volume of packed erythrocytes given, mL600 (2 units)0.2
Postoperative recovery
Length of hospital stay, mean ± SD; d5.30 ± 2.485.31 ± 2.820.3
Composite complication rate, %06.90.02
Pulmonary embolism0 (0)2 (3)0.08
Infection0 (0)2 (3)0.08
Discharged to rehabilitation2 (4)12 (21)0.004
  • SD = standard deviation.

  • * Except where noted otherwise.

  • Paired t test.