Perioperative outcomes recorded in matched pairs of older patients (age ≥ 65 yr)
| Outcome | No. (%) of patients* | p value† | |
|---|---|---|---|
| Control group n = 58 | Tranexamic acid group n = 58 | ||
| Hematologic | |||
| Preoperative hemoglobin level, mean ± SD; g/L | 131.07 ± 11.58 | 132.67 ± 11.31 | 0.4 |
| Lowest postoperative hemoglobin level, mean ± SD; g/L | 89.53 ± 10.20 | 99.79 ± 10.43 | < 0.001 |
| % decrease in hemoglobin level, mean ± SD | 31.56 ± 6.14 | 24.65 ± 6.27 | < 0.001 |
| Estimated total blood loss, mean ± SD; mL | 1618 ± 448 | 1208 ± 407 | < 0.001 |
| Packed erythrocytes transfusion | 3 (5) | 1 (2) | 0.6 |
| Total volume of packed erythrocytes given, mL | 2100 (7 units) | 600 (2 units) | 0.3 |
| Postoperative recovery | |||
| Length of hospital stay, mean ± SD; d | 6.24 ± 3.62 | 5.31 ± 2.82 | 0.05 |
| Composite complication rate, % | 8.6 | 6.9 | 0.4 |
| Deep vein thrombosis | 2 (3) | 0 (0) | 0.1 |
| Pulmonary embolism | 2 (3) | 2 (3) | 0.5 |
| Infection | 1 (2) | 2 (3) | 0.3 |
| Discharged to rehabilitation | 11 (19) | 12 (21) | 0.4 |