Univariate and multivariate analysis of predictive factors for postoperative acute kidney injury according to creatinine output and urine output criteria
| Factor | Univariate analysis, creatinine criterion* | Multivariate analysis, creatinine criterion* | Univariate analysis, urine output criterion† | |||
|---|---|---|---|---|---|---|
| OR | p value | OR (95%CI) | p value | OR (95%CI) | p value | |
| Age | 1.07 | 0.03 | 1.10 (1.02–1.19) | 0.02 | 1.03 (1.00–1.07) | 0.20 |
| Sex | 1.62 | 0.51 | — | — | 0.41 (0.14–1.17) | 0.12 |
| BMI ≥ 30 | 2.78 | 0.14 | — | — | 3.90 (1.00–15.25) | 0.07 |
| ASA ≥ 3 | 1.47 | 0.55 | — | — | 2.32 (0.85–6.33) | 0.14 |
| Hypertension | 4.07 | 0.19 | — | — | 1.67 (0.65–4.29) | 0.35 |
| Diabetes | 2.93 | 0.11 | — | — | 1.14 (0.41–3.17) | > 0.99 |
| Coronary artery disease | 1.81 | 0.42 | — | — | 0.89 (0.24–3.35) | > 0.99 |
| Preoperative eGFR < 60 mL/min | 2.78 | 0.14 | — | — | 1.70 (0.53–5.45) | 0.39 |
| Cirrhosis | 0.51 | 0.45 | — | — | 1.24 (0.39–3.95) | 0.77 |
| Surgery (minor v. major) | 4.33 | 0.02 | 1.87 (0.37–9.45) | 0.45 | 4.89 (1.46–16.36) | < 0.01 |
| Laparoscopic | 0.29 | 0.45 | — | — | 0.48 (0.14–1.61) | 0.24 |
| Pringle | 1.65 | 0.48 | — | — | 2.84 (0.81–9.92) | 0.15 |
| EBL | 1.003 | < 0.01 | 1.002 (1.000–1.005) | 0.07 | 1.001 (1.000–1.003) | 0.18 |
ASA = American Society of Anesthesiologists; BMI = body mass index; CI = confidence interval; EBL = estimated blood loss; eGFR = estimated glomerular filtration rate; OR = odds ratio.
↵* Relative (1.5 times) or absolute (≥ 0.3 mg/dL or ≥ 26.5 μmol/L) increase in baseline serum creatinine value.
↵† Mean 8-h urine output < 0.5 mL/kg/h.