Comparison of baseline characteristics and clinical outcomes between patients with retroperitoneal liposarcoma extending to inguinal canal and patients with inguinoscrotal liposarcoma.
| Characteristic | Group; no. (%), or mean ± SD* | p value | |
|---|---|---|---|
| Retroperitoneal LPS (n = 6) | Inguinoscrotal LPS (n = 7) | ||
| Male sex | 5 (83.3) | 6 (85.7) | > 0.99 |
| Age, yr | 49.7 ± 6.4 | 52.1 ± 12.5 | 0.37 |
| Laterality, right:left | 3:3 | 4:3 | > 0.99 |
| Scrotal involvement | 2 (40.0) | 4 (66.7) | 0.57 |
| Tumour size, cm | 27.9 ± 6.8 | 7.8 ± 4.2 | 0.001 |
| Combined organ resection | 5 (83.3) | 2 (28.6) | 0.10 |
| Histology | 0.52 | ||
| Well-differentiated liposarcoma | 2 (33.3) | 1 (14.3) | |
| De-differentiated liposarcoma | 4 (66.7) | 5 (71.4) | |
| Round/myxoid liposarcoma | 0 (0) | 1 (14.3) | |
| Grade (I:II:III) | 1:1:1 | 4:2:0 | 0.35 |
| Margin positive, % | 100 | 66.7 | > 0.99 |
| Postoperative complications | 4 (66.7) | 0 (0) | 0.021 |
| Comprehensive complication index, median [IQR) | 8.7 [0–21.72] | — | 0.05 |
| Adjuvant therapy | 4 (66.7) | 6 (85.7) | 0.56 |
| Recurrence | 4 (66.7) | 5 (71.4) | > 0.99 |
| Recurrence-free duration, mo, median (IQR) | 12.5 [1.75–37.25] | 18.0 [7.0–47.0] | 0.73 |
| No. of recurrences, median (IQR) | 2.0 [0–4.25] | 1.0 [0–5.0] | 0.74 |
| Local:distant recurrence | 3:1 | 4:1 | > 0.99 |
| Death | 2 (33.3) | 0 (0) | 0.19 |
| Survival, mo | 44.3 ± 36.4 | 71.4 ± 68.2 | 0.35 |
| Progression to inoperable status | 4 (66.7) | 0 (0) | 0.021 |
| Death | 2 (33.3) | 0 (0) | 0.19 |
| Inoperable progression | 2 (33.3) | 0 (0) | 0.19 |
| Disease-free status | 2 (33.3) | 7 (100) | 0.021 |
IQR = interquartile range; LPS = liposarcoma; SD = standard deviation.
↵* Unless indicated otherwise.