Table 1

Effect of rutin and L-NIL on plasma nitrite/nitrate and cyclic guanosine monophosphate production mediated by renal ischemia/reperfusion

Group	Plasma cGMP, mean (SD) pmol/mL	Percent change	Plasma nitrite/nitrate, mean (SD) μmol/L	Percent change
Sham	5.56 (0.09)^*^†	—	5.6 (0.31)^*	—
Sham+NP	5.78 (0.09)^*^†	+ 3.9	5.3 (0.83)^*	−5.3
NP+I/R	9.73 (0.05)^†^‡	+ 75	13.21 (0.8)^†^‡	+ 135
NP+L-NIL+I/R	6.86 (0.10)^*^‡	+ 23	5.9 (0.61)^*	+ 5.3
NP+rutin+I/R	6.56 (0.10)^*^‡	+ 17	5.6 (0.46)^*	—

↵cGMP = cyclic guanosine monophosphate; I/R = ischemia/reperfusion; L-NIL = L-N6-(1-iminoethyl)lysine; NP = nephrectomy; SD = standard deviation.
↵* p < 0.05 v. NP+I/R group.
↵† p < 0.05 v. NP+L-NIL+I/R group; p < 0.05 v. NP+rutin+I/R group.
↵‡ p < 0.05 v. sham group; p < 0.05 v. sham+NP group.