Univariate analysis of factors associated with local recurrence and disease-specific survival
| Variable | 5-year LR, % | p value | 5-year DSS, % | p value |
|---|---|---|---|---|
| Group | 0.61 | 0.07 | ||
| High-volume, colorectal | 92.1 | 87.9 | ||
| High-volume, no subspecialty training | 91.3 | 75 | ||
| Low-volume, no subspecialty training | 93.4 | 84.7 | ||
| Obstruction | < 0.001 | < 0.001 | ||
| Yes | 54.7 | 34.2 | ||
| No | 93.4 | 84.2 | ||
| Tumour level | 0.66 | 0.31 | ||
| Low | 89.7 | 84.5 | ||
| Mid | 93.2 | 87.7 | ||
| High | 92.6 | 97.4 | ||
| Blood transfusion | 0.22 | 0.14 | ||
| Yes | 93.7 | 80.4 | ||
| No | 89.9 | 84.2 | ||
| Perforation | 0.34 | 0.57 | ||
| Yes | 100 | 71.6 | ||
| No | 92.1 | 83.1 | ||
| Stage | 0.044 | < 0.001 | ||
| 1 | 95.9 | 96 | ||
| 2 | 92.9 | 86.4 | ||
| 3 | 88.2 | 65.5 | ||
| Grade | 0.10 | 0.005 | ||
| 1 | 100 | 90.7 | ||
| 2 | 92.0 | 83.8 | ||
| 3 | 86.0 | 69.2 | ||
| LVI/PNI | 0.08 | 0.001 | ||
| Yes | 86.1 | 70 | ||
| No | 93.4 | 84 | ||
| Operation | 0.34 | 0.028 | ||
| LAR | 90.8 | 85 | ||
| APR | 93.5 | 79.7 | ||
| Age, yr | 0.11 | 0.17 | ||
| < 40 | 98 | 89.5 | ||
| 40–59 | 95.2 | 85.6 | ||
| 60–79 | 89.4 | 80 | ||
| ≥ 80 | 94.4 | 83.9 | ||
| Radial margin < 1 mm | 0.30 | 0.040 | ||
| Yes | 92.3 | 72.7 | ||
| No | 89.9 | 84.3 | ||
| Distal margin < 2 cm | 0.09 | 0.34 | ||
| Yes | 95.1 | 79 | ||
| No | 89.3 | 83 | ||
| Neoadjuvant/adjuvant therapy | 0.51 | 0.008 | ||
| Yes | 91.2 | 78.5 | ||
| No | 94.1 | 89.6 | ||
| Hospital | 0.15 | 0.07 | ||
| 1 | 87.9 | 76.2 | ||
| 2 | 91.9 | 88.8 | ||
| 3 | 93.8 | 87.1 | ||
| 4 | 91.9 | 79.4 | ||
| 5 | 95.2 | 98.9 | ||
| 6 | 97.4 | 88.7 |
APR = abdominoperineal resection; DSS = disease specific survival; LAR = lower anterior resection; LR = local recurrence; LVI = lymphovascular space invasion; PNI = perineural invasion.