Effects of vitamin E on histopathologic and antioxidant parameters in an acetic acid–induced colitis model
| Parameter | Group; mean (SE) | p value | |||
|---|---|---|---|---|---|
| Saline, n = 8 | Vitamin E, n = 8 | AA, n = 8 | AA + vitamin E, n = 8 | ||
| Macroscopic score | 0 (0) | 0 (0) | 4.7 (0.34) | 2.8 (1.06) | < 0.001 |
| Microscopic score | 0.1 (0.28) | 0.1 (0.24) | 7.6 (1.28) | 3.2 (0.97) | < 0.001 |
| GSH, μmol/mg protein | 1.9 (1.1) | 2.1 (1) | 0.2 (0.6) | 2.0 (1.2) | < 0.001 |
| SOD, U/mg protein | 8.7 (2.3) | 9.5 (3.8) | 1.2 (2) | 9.8 (4.2) | < 0.001 |
AA = acetic acid; GSH = glutathione peroxidase; SE = standard error; SOD = superoxide dismutase.