Table 5

Operative time of open and laparoscopic surgeries

Trial	Operative time; median (range) or mean ± SD, min		p value
Trial	Open surgery	Laparoscopic surgery	p value
Colon cancer
COLOR10	115 (70–180)	145 (102–230)	< 0.001
COST16	95 (27–435)	150 (35–450)	< 0.001
Barcelona23	118 ± 45	142 ± 52	0.001
Liang et al.24	184 ± 31	224 ± 45	< 0.001
LAPKON II26	138 ± 45	183 ± 61	< 0.001
ALCCaS27	107 (45–250)	158 (49–365)	< 0.001
Rectal cancer
Liang et al.33	119 ± 22	138 ± 24	< 0.001
COREAN34	197 ± 63	245 ± 75	< 0.001
Lujan et al.36	173 ± 59	194 ± 45	0.020
Ng et al.37	154 ± 70	213 ± 59	< 0.001
Ng et al.39	164 ± 43	214 ± 46	< 0.001
Braga et al.41	209 ± 70	262 ± 72	< 0.001
Zhou et al.42	106 (80–230)	120 (110–220)	0.05

ALCCaS = Australasian Laparoscopic Colon Cancer Study; COLOR = Colon cancer Laparoscopic or Open Resection; COREAN = Comparison of Open versus laparoscopic surgery for mid and low Rectal cancer After Neoadjuvant chemoradiotherapy; COST = Clinical Outcomes of Surgical Therapy; SD = standard deviation.