Factor | Group; mean ± SD or no. (%)* | p value† | ||
---|---|---|---|---|
Overall, n = 208 | UNE, n = 138 | BNE, n = 70 | ||
Age, yr | 58.6 ± 13.5 | 59.3 ± 14.2 | 57.1 ± 12.2 | 0.26 |
Sex, female | 156 (75.0) | 103 (74.6) | 53 (74.7) | 0.87 |
Preoperative Ca, mmol/L | 2.75 ± 0.19 | 2.76 ± 0.18 | 2.73 ± 0.19 | 0.19 |
Intraoperative PTH assay | 139 (66.8) | 101 (73.2) | 38 (54.3) | 0.006 |
PTH, nmol/L | 19.8 ± 25.9 | 22.6 ± 28.9 | 14.4 ± 17.5 | 0.032 |
Greatest dimension, cm | 1.76 ± 1.02 | 1.91 ± 1.17 | 1.50 ± 0.61 | 0.011 |
Adenoma type | 0.002 | |||
Solitary | 191 (91.8) | 133 (96.3) | 58 (82.9) | — |
Double | 5 (2.4) | 0 (0) | 5 (7.1) | — |
Ectopic | 7 (3.4) | 4 (3.0) | 3 (4.3) | — |
Hyperplasia | 3 (1.4) | 0 (0) | 3 (4.3) | — |
Carcinoma | 2 (1.0) | 1 (0.7) | 1 (1.4) | — |
Imaging studies | 0.007 | |||
Group I | 75 (36.0) | 41 (29.7) | 34 (48.6) | — |
SPECT only | 61 (29.3) | 28 (20.3) | 33 (47.2) | — |
SPECT/CT | 14 (6.7) | 13 (9.4) | 1 (1.4) | — |
Group II | 133 (64.0) | 97 (70.3) | 36 (51.4) | — |
SPECT+ ultrasonography | 62 (29.8) | 42 (30.4) | 20 (28.6) | — |
SPECT/CT+ ultrasonography | 71 (34.1) | 55 (39.9) | 16 (22.8) | — |
BNE = bilateral neck exploration; Ca = calcium; CT = computed tomography; PTH = parathyroid hormone; SD = standard deviation; SPECT = single photon emission computed tomography; UNE = unilateral neck exploration.
↵* Unless otherwise indicated.
↵† The p value for differences between UNE and BNE was calculated using a 2-sided t test (continuous data) and χ2 test (categorical data).