Table 4

Symptom attributes for vascular intermittent claudication

Attribute*Measure (95% CI)
SensitivitySpecificityPLRNLR
Single symptom attribute
Trigger
 Walking (2)0.96 (0.76–1.00)0.10 (0.03–0.28)1.10 (0.92–1.2)0.43 (0.04–5.3)
Symptom onset
 Predictable (2a)0.87 (0.65–0.97)0.37 (0.21–0.56)1.37 (1.0–1.9)0.36 (0.11–1.1)
Alleviator
 Standing (3)0.78 (0.56–0.92)0.90 (0.72–0.97)7.80 (2.6–23)0.24 (0.11–0.53)
Nature
 Numbness (8)0.59 (0.37–0.79)0.25 (0.11–0.45)0.79 (0.52–12)1.60 (0.80–3.3)
 Cramping (9)0.65 (0.43–0.83)0.47 (0.29–0.65)1.20 (0.78–1.9)0.75 (0.40–1.9)
 Burning pain (10)0.47 (0.27–0.69)0.38 (0.21–0.58)0.77 (0.46–1.3)1.37 (0.83–2.3)
 Weakness (11)0.41 (0.21–0.63)0.57 (0.37–0.75)0.95 (0.49–1.8)1.00 (0.69–1.5)
Location
 Calves (6)0.78 (0.56–0.92)0.73 (0.54–0.87)2.90 (1.6–5.5)0.30 (0.13–0.66)
Time for relief
 1–2 min (11a)0.57 (0.35–0.76)0.57 (0.38–0.74)1.30 (0.76–2.2)0.77 (0.46–1.3)
Constellation of symptom attributes
Alleviated with Standing (3), located in the calves (6)0.65 (0.43–0.83)0.97 (0.81–1.0)20.00 (2.8–140)0.36 (0.21–0.63)
  • CI = confidence interval; NLR = negative likelihood ratio; PLR = positive likelihood ratio.

  • * Numbers in brackets represent the corresponding question number in the questionnaire (see the Appendix, available at cma.ca/cjs).

  • Numbers whose value represent clinical significance.