Factors that affected survival after surgery in 36 patients with gastrointestinal stromal tumours
| Factor | No. (%) patients | Survival; % | Median survival, yr | p values | |||
|---|---|---|---|---|---|---|---|
| 1-yr | 3-yr | 5-yr | Log-rank | Cox* | |||
| Cumulative survival | 88.9 | 61.7 | 49.4 | 53.0 | |||
| Age, yr | |||||||
| ≤ 60 | 19 (52.8) | 94.7 | 76.5 | 76.5 | 70.0 | 0.011 | 0.69 |
| > 60 | 17 (47.2) | 94.7 | 46.3 | 37.1 | 31.0 | ||
| Sex | |||||||
| Female | 15 (41.7) | 86.7 | 45.7 | 15.2 | 36.0 | 0.05 | 0.51 |
| Male | 21 (58.3) | 90.5 | 74.4 | 66.9 | 70.0 | ||
| Accompanying disease | |||||||
| Positive | 10 (27.8) | 80.0 | 57.1 | 57.1 | 55.0 | 0.55 | |
| Negative | 26 (72.2) | 92.3 | 63.2 | 38.3 | 53.0 | ||
| Tumour location | |||||||
| Stomach | 19 (52.8) | 89.5 | 71.6 | 55.7 | 70.0 | 0.16 | |
| Small intestines | 11 (30.6) | 90.9 | 71.6 | 57.3 | 57.3 | ||
| Colon and rectum | 6 (16.7) | 66.7 | 16.7 | — | 10.0 | ||
| Tumour diameter | |||||||
| ≤ 5 cm | 15 (41.7) | 93.3 | 86.7 | 57.8 | 70.0 | 0.029 | 0.25 |
| > 5 cm | 21 (58.3) | 80.9 | 43.4 | 37.9 | 31.0 | ||
| Fletcher classification | |||||||
| Low | 6 (16.7) | 100 | 100 | 100 | 100 | 0.022 | 0.34 |
| Intermediate | 16 (44.4) | 93.7 | 61.9 | 61.9 | 70.0 | ||
| High | 14 (38.9) | 78.6 | 43.6 | 11.6 | 36.0 | ||
| Mitosis count | |||||||
| ≤ 5/10 HPF | 18 (50.0) | 94.4 | 70.3 | 70.3 | 70.0 | 0.09 | |
| > 5/10 HPF | 18 (50.0) | 83.3 | 52.9 | 27.8 | 41.0 | ||
| Invasion/metastasis | |||||||
| No | 18 (50.0) | 94.4 | 64.8 | 43.2 | 53.0 | 0.70 | |
| Yes | 18 (50.0) | 77.8 | 58.3 | 50.0 | 41.0 | ||
| Resection | |||||||
| Complete | 27 (75.0) | 100 | 76.3 | 61.0 | 70.0 | < 0.001 | < 0.001 |
| Incomplete | 9 (25.0) | 55.6 | 13.9 | 0 | 25.0 | ||
| Distant metastasis† | |||||||
| Positive | 7 (19.4) | 100 | 34.3 | 0 | 31.0 | < 0.001 | 0.07 |
| Negative | 20 (55.5) | 100 | 89.4 | 79.5 | 70.0 | ||
| Local recurrence† | |||||||
| Positive | 6 (16.7) | 100 | 20.0 | 0 | 31.0 | < 0.001 | 0.81 |
| Negative | 21 (58.3) | 100 | 90.5 | 80.4 | 70 | ||