Study population characteristics
| Characteristic | No. (%) of patients* | p value | |
|---|---|---|---|
| Early era n = 32 | Late era n = 38 | ||
| Donors | |||
| Demographic | |||
| Age, yr, median (IQR) | 44 (18–62) | 38 (12–59) | 0.1 |
| Male sex | 16 (50) | 28 (74) | 0.04 |
| Height, cm, median (IQR) | 169 (150–193) | 175 (152–188) | 0.1 |
| Weight, kg, mean ± SD | 76 ± 5.6 | 75 ± 14.6 | 0.49 |
| Body mass index, median (IQR) | 25 (17–46) | 24 (17–35) | 0.2 |
| Donor Risk Index score, median (IQR) | 2.46 (1.7–3.2) | 2.1 (1.6–3.4) | 0.02 |
| Location | 0.04 | ||
| Local | 15 (47) | 27 (71) | |
| Regional | 17 (53) | 11 (29) | |
| Cause of death | 0.049 | ||
| Trauma | 13 (41) | 15 (39) | |
| Anoxia | 6 (19) | 16 (42) | |
| Cerebrovascular accident | 13 (41) | 7 (18) | |
| Procurement times | |||
| Warm ischemia time, min, median (IQR) | 27 (18–121) | 24 (16–48) | 0.049 |
| Cut–cannulation–flush, min, median (IQR) | 6 (2–12) | 4 (2–8) | 0.02 |
| Skin cut to liver out, min, median (IQR) | 56 (21–97) | 52 (28–121) | 0.2 |
| Cold ischemia time, h, median (IQR) | 5.56 (4.45–6.45) | 5.10 (4.46–6.37) | 0.4 |
| Recipients | |||
| Demographic | |||
| Age, yr, median (IQR) | 54 (26–69) | 57 (36–66) | 0.3 |
| Male sex | 26 (81) | 26 (68) | 0.2 |
| MELD score, median (IQR) | 15 (8–40) | 17 (3–35) | 0.7 |
| Diagnosis | 0.003 | ||
| Hepatitis C | 12 (38) | 4 (10) | |
| Hepatocellular carcinoma | 8 (25) | 15 (39) | |
| Alcoholic liver disease | 5 (16) | 2 (5) | |
| Autoimmune | 3 (9) | 0 (0) | |
| Nonalcoholic steatohepatitis | 0 (0) | 5 (13) | |
| Primary biliary cirrhosis | 0 (0) | 3 (8) | |
| Primary sclerosing cholangitis | 0 (0) | 3 (8) | |
| Other | 4 (12) | 6 (16) | |
IQR = interquartile range; MELD = Model for End-Stage Liver Disease; SD = standard deviation.
↵* Except where noted otherwise.