Characteristics of patients with stage 3 cancer
| Characteristic | Cohort; no. (%) of patients* | p value | |
|---|---|---|---|
| 1996, n = 89 | 2003/04, n = 148 | ||
| Age, yr, mean (range) | 66.6 (41–86) | 65.2 (32–92 | 0.18 |
| Sex | 0.98 | ||
| Female | 35 (39.3) | 58 (39.1) | |
| Male | 54 (60.6) | 90 (60.8) | |
| Distance from anal verge | 0.036 | ||
| Distal (< 5 cm) | 20 (22.4) | 56 (37.8) | |
| Mid (5–10 cm) | 46 (51.6) | 56 (37.8) | |
| Upper (> 10 cm) | 23 (25.8) | 36 (24.3) | |
| Type of resection | 0.57 | ||
| Anterior and Hartmann | 52 (58.4) | 92 (62.1) | |
| Abdominoperineal | 37 (41.5) | 56 (37.8) | |
| Circumferential resection margin | < 0.001 | ||
| Positive | 7 (7.8) | 27 (18.2) | |
| Negative | 49 (55.0) | 117 (79.0) | |
| Unknown | 33 (37.0) | 4 (2.7) | |
| Radiotherapy | 0.17† | ||
| None | 27 (30.3) | 33 (22.2) | |
| Radiotherapy | 62 (69.7) | 115 (77.7) | |
| Preoperative | 4 (4.4) | 91 (61.4) | < 0.001‡ |
| Postoperative | 58 (65.1) | 24 (16.2) | |