Characteristics of study population
| Variable | Study group; no. (%) of patients* | p value | |
|---|---|---|---|
| TXA n = 31 | Control n = 34 | ||
| Age, yr, mean ± SD | 80.32 ± 10.73 | 79.03 ± 10.42 | 0.62† |
| Sex, female | 20 (64.5) | 25 (73.5) | 0.59‡ |
| Smoker | 13 (41.9) | 5 (14.7) | 0.025‡ |
| BMI, mean ± SD | 25.08 ± 7.23 | 25.94 ± 5.62 | 0.60† |
| Charlson Comorbidity Index score, mean ± SD | 4.35 ± 1.72 | 4.65 ± 1.97 | 0.53† |
| Fracture type | |||
| Intracapsular | 13 (41.9) | 12 (35.3) | |
| Intertrochanteric | 17 (54.8) | 19 (55.9) | |
| Subtrochanteric | 0 (0) | 2 (5.9) | 0.57§ |
| Unknown | 1 (3.2) | 1 (2.9) | |
| Treatment modality | |||
| DHS | 2 (6.4) | 3 (8.8) | |
| Hemiarthroplasty | 11 (35.5) | 10 (29.4) | |
| IMN | 2 (6.4) | 2 (5.9) | 0.86§ |
| ORIF | 1 (3.2) | 4 (11.8) | |
| TFN | 13 (41.9) | 13 (38.2) | |
| THA | 2 (6.4) | 2 (5.9) | |
| ASA classification | |||
| 2 | 2 (6.4) | 2 (5.9) | |
| 3 | 20 (64.5) | 18 (52.9) | 0.59§ |
| 4 | 9 (29.0) | 14 (41.2) | |
| Baseline eGFR, mean ± SD | 87.29 ± 26.7 | 71.88 ± 22.5 | 0.015† |
| Baseline hemoglobin, mean ± SD | 123.35 ± 16.1 | 122.03 ± 17.2 | 0.75† |
ASA = American Society of Anesthesiologists; BMI = body mass index; DHS = dynamic hip screw; eGFR = estimated glomerular filtration rate; IMN = intramedullary nail; SD = standard deviation; THA = total hip arthroplasty; TFN = trochanteric fixation nail; TXA = tranexamic acid.
↵* Unless indicated otherwise.
↵† From t test.
↵‡ From Fisher exact test.
↵§ From Pearson χ2 test.