Transfusion data between groups*
Variable | TXA n = 31 | Control n = 34 | p value |
---|---|---|---|
Transfusion, no. (%) | 2 (6.4) | 5 (14.7) | 0.43† |
Total no. of units of pRBC transfused | 2 | 8‡ | 0.024§ |
pRBC = packed red blood cells; TXA = tranexamic acid.
↵* All patients receiving blood after study enrolment were included. Transfusion trigger parameters were hemoglobin level less than 70 g/L, or hemogloblin level less than 80 g/L with symptoms of hypoperfusion.
↵† From Fisher exact test.
↵‡ One patient in the control group who had a subtrochanteric fracture required an open reduction and received 2 units of pRBC intraoperatively because of hemodynamic instability (i.e., outside of the transfusion parameters), followed by 1 unit of pRBC on postoperative day 1. When the 2 units of pRBC given intraoperatively are excluded, the numbers of units transfused between the groups are no longer significantly different (p = 0.07).
↵§ From χ2 test.