Univariate and multivariate analysis for predictors of overall axillary pathologic complete response
| Predictor | OR (95% Cl) | |
|---|---|---|
| Univariate analysis | Multivariate analysis | |
| Histologic type | ||
| Lobular (Ref) | 1 | 1 |
| Ductal | 4.43 (0.99–19.89) | 2.16 (0.18–26.15) |
| Mixed ductal/lobular | —* | —* |
| Receptor subtype | ||
| ER+/PR+/HER2− (Ref) | 1 | 1 |
| ER+/PR−/HER2− | 3.42 (1.42–8.22) | 2.16 (0.60–7.70) |
| HER2+ | 5.04 (2.72–9.33) | 2.41 (0.90–6.48) |
| Triple-negative | 3.82 (1.89–7.70) | 2.39 (0.88–6.54) |
| Tumour grade | ||
| Low (1–2) (Ref) | 1 | 1 |
| High (3) | 2.11 (1.27–3.51) | 1.78 (0.80–3.94) |
| Nodal density | ||
| Multiple (Ref) | 1 | — |
| Single | 1.11 (0.61–2.03) | — |
| Residual tumour | ||
| Yes (Ref) | 1 | 1 |
| No | 7.28 (4.31–12.29) | 6.74 (2.89–15.67) |
| Tumour size | 0.93 (0.81–1.06) | 0.91 (0.76–1.08) |
CI = confidence interval; ER = estrogen receptor; HER2 = human epidermal growth factor receptor 2; OR = odds ratio; PR = progesterone receptor; Ref = reference.
↵* Could not be determined.