Patients’ clinical characteristics
| Characteristic | No. (%*) of patients† | Test coefficient | p value‡ | |
|---|---|---|---|---|
| Platelet transfusion | No platelet transfusion | |||
| Glasgow Coma Scale score, median (IQR) | 15.0 (13.0–15.0) | 15.0 (12.8–15.0) | U = 897.5 | 0.99 |
| ICU length of stay, median (IQR), d | 2.0 (1.0–6.0) | 1.0 (0.0–5.3) | U = 6329.5 | 0.01 |
| International normalized ratio, median (IQR) | 1.05 (0.98–1.10) | 1.02 (0.97–1.08) | U = 3643.5 | 0.8 |
| Injury Severity Score, median (IQR) | 17.0 (16.0–25.0) | 16.0 (12.3–18.0) | U = 6588.5 | 0.002 |
| Antiplatelet medication | χ22 = 4.906 | 0.09 | ||
| ASA and clopidogrel | 28 (17.9) | 5 (7.4) | ||
| Clopidogrel | 15 (9.6) | 5 (7.4) | ||
| ASA | 113 (72.4) | 58 (85.3) | ||
| Infection | 13 (9.2) | 5 (7.8) | χ21 = 0.109 | 0.7 |
| Infection other than urinary tract infection | 5 (3.6) | 5 (3.6) | Exact | 0.7 |
| Mechanism of injury | χ21 = 0.268 | 0.6 | ||
| Fall | 130 (83.3) | 55 (80.9) | ||
| Other | 19 (12.2) | 10 (14.7) | ||
| Missing/unknown | 7 (4.5) | 3 (4.4) | ||
| In-hospital death | 12 (7.7) | 1 (1.5) | Exact | 0.1 |
| Operative intervention | 22 (14.1) | 6 (8.8) | χ21 = 1.207 | 0.3 |
| Repeat tICH changes on brain CT | χ22 = 2.304 | 0.3 | ||
| Increased | 28 (17.9) | 9 (13.2) | ||
| No change | 95 (60.9) | 42 (61.8) | ||
| Decrease | 10 (6.4) | 8 (11.8) | ||
| Missing/unknown | 23 (14.7) | 9 (13.2) | ||
| Respiratory failure | 6 (3.8) | 4 (5.9) | Exact | 0.5 |
| Renal failure | 5 (3.2) | 6 (8.8) | Exact | 0.09 |
| Skull fracture | 12 (7.7) | 3 (4.4) | Exact | 06 |
| Transfusion complication | 1 (0.7) | — | ||
ASA = acetylsalicylic acid; CT = computed tomography; ICU = intensive care unit; IQR = interquartile range; tICH = traumatic intracranial hemorrhage.
↵* Proportions do not reflect missing values.
↵† Except where noted otherwise.
↵‡ Obtained from Mann–Whitney U test, χ2 test or Fisher exact test where applicable.