Table 1

Society SLNB recommendations

SocietyYearBreslow depthSLNB recommendation
NCCN2019< 0.8 mm without ulcerationNot recommended
< 0.8 mm with ulcerationDiscuss and consider
0.8–1.0 mmDiscuss and consider
> 1.0 mmRecommended
ASCO-SSO2018< 0.8 mm without ulcerationNot recommended
< 0.8 mm with ulcerationDiscuss and consider
0.8–1.0 mmDiscuss and consider
1.01–4.0 mmRecommended
> 4.0 mmMay be recommended
ESMO2019< 0.8 mm without ulcerationNot recommended
< 0.8 mm with ulcerationRecommended
0.8–1.0 mmRecommended
> 1.0 mmRecommended
CCO2019< 0.8 mm without ulcerationNot recommended
< 0.8 mm with high-risk features*Discuss and consider
0.8–1.0 mmDiscuss and consider
1.01–4.0 mmRecommended
> 4.0 mmDiscuss and consider

  • ASCO-SSO = American Society of Clinical Oncology and Society of Surgical Oncology; CCO = Cancer Care Ontario clinical practice guideline22; ESMO = European Society for Medical Oncology; NCCN = National Comprehensive Cancer Network; SLNB = sentinel lymph node biopsy.

  • ↵* High-risk features include Clark level IV or V, mitotic rate ≥ 1/ mm2, ulceration or microsatellites.