Characteristics of study population
| Characteristic | No. (%) of patients* n = 759 |
|---|---|
| Age, yr | |
| < 50 | 128 (16.9) |
| 50–75 | 401 (52.8) |
| > 75 | 230 (30.3) |
| Female | 330 (43.5) |
| Location of primary tumour | |
| Extremity | 333 (43.9) |
| Trunk | 255 (33.6) |
| Head and neck | 171 (22.5) |
| Definitive wide local excision | 718 (94.6) |
| Breslow depth, mm | |
| ≤ 1.0 | 189 (24.9) |
| 1.01–4.0 | 429 (56.5) |
| > 4.0 | 141 (18.6) |
| Ulceration | 172 (22.7) |
| Mitotic rate (mitoses/mm2) | |
| < 1 | 160 (21.1) |
| ≥ 1 | 599 (78.9) |
| Lymphovascular invasion | 19 (2.5) |
| Clinical stage† | |
| IA | 96 (12.6) |
| IB | 347 (45.7) |
| IIA | 134 (17.7) |
| IIB | 96 (12.6) |
| IIC | 85 (11.2) |
| Clinical stage‡ | |
| IA | 9 (11.9) |
| IB | 435 (57.3) |
| IIA | 132 (17.4) |
| IIB | 97 (12.8) |
| IIC | 85 (11.2) |
↵* Percentages in some categories may sum to less than 100% because of missing data.
↵† TNM stage determined on the basis of the seventh edition of the American Joint Committee on Cancer’s AJCC Cancer Staging Manual.
↵‡ TNM stage determined on the basis of the eighth edition of the American Joint Committee on Cancer’s AJCC Cancer Staging Manual.