Table 1

Demographic and clinical characteristics of the study cohort

Characteristic	All patients, no.^*	Local disease, no.^*	Metastatic disease, no.^*	p value
No. (%) of patients	304	234 (77)	70 (23)	—
Age, yr, mean ± SD	11.0	10.87 ± 3.0	11.39 ± 2.5	0.19
Gender				0.10
Male	143	104	39	—
Female	161	130	31	—
Ethnicity				0.50
Arab	10	8	< 5	—
Asian	36	27	9	—
Black	10	8	< 5	—
Indigenous	11	11	< 5	—
Not available	42	29	13	—
Other	9	6	< 5	—
White	186	145	41	—
Location of primary				0.72
Bones of upper extremity	42	32	10	—
Bones of lower extremity	237	183	54	—
Other	25	19	6	—
Morphology				0.59
Osteosarcoma NOS	241	184	57	—
Central	26	18	8	—
Telangiectatic	14	12	< 5	—
High grade surface	7	6	< 5	—
Chondroblastic	13	12	< 5	—
Other	< 5	< 5	< 5	—