Skip to main content
Log in

Intra-articular hip injection: does pain relief correlate with radiographic severity of osteoarthritis?

  • Scientific Article
  • Published:
Skeletal Radiology Aims and scope Submit manuscript

An Erratum to this article was published on 28 June 2012

Abstract

Objective

Intra-articular injection is being used widely for both diagnostic and therapeutic purposes in the hip. However, its efficacy is not always predictable in patients with hip osteoarthritis (OA). The purpose of this study was to determine whether the degree of radiographic severity of OA was predictive of the response to intra-articular injection of local anesthetic with corticosteroid and to determine the relationship between immediate pain relief resulting from the anesthetic and delayed pain relief resulting from corticosteroid administration.

Materials and methods

This retrospective study included 217 patients (220 injections) with diagnosis of hip OA who underwent a fluoroscopically guided therapeutic hip injection of local anesthetic and corticosteroid. Hip radiographs were scored using the Kellgren–Lawrence scale. Immediate and delayed pain relief was documented using a visual analog scale. Logistic regression analysis was performed to investigate whether age, gender or radiographic severity of OA were independent predictors of pain relief. Degree of agreement between immediate and delayed response was assessed with the kappa coefficient.

Results

Immediate pain relief was reported in 68.2% of hips and delayed relief in 71.4% of hips. A high level of agreement was observed between immediate and delayed pain relief (kappa = 0.80, p < 0.001). 94% of patients reporting immediate relief also reported relief 2 weeks later. Univariate and multivariate analysis revealed that neither gender nor age was related to immediate or delayed pain relief. Only severity of OA (based on radiographic analysis) was observed to be predictive of pain relief.

Conclusion

Pain relief following intra-articular hip injection correlated with radiographic severity of OA. This intervention may be of therapeutic and prognostic value in patients awaiting hip arthroplasty.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2

Similar content being viewed by others

References

  1. Lawrence JS, Bremner JM, Bier F. Osteoarthrosis: prevalence in the population and relationship between symptoms and x-ray changes. Ann Rheum Dis. 1966;25:1–24.

    Article  CAS  Google Scholar 

  2. Creamer P. Intra-articular corticosteroid treatment in osteoarthritis. Curr Opin Rheumatol. 1999;11(5):417–21.

    Article  CAS  Google Scholar 

  3. Kleiner JB, Thorne RP, Curd JG. The value of bupivicaine hip injection in the differentiation of coxarthrosis from lower extremity neuropathy. J Rheumatol. 1991;18:422–7.

    CAS  PubMed  Google Scholar 

  4. Crawford RW, Gie GA, Ling RSM, Murray DW. Diagnostic value of intra-articular anaesthetic in primary osteoarthritis of the hip. J Bone Joint Surg Br. 1998;80:279–81.

    Article  CAS  Google Scholar 

  5. Faraj AA, Kumaraguru P, Kosygan K. Intra-articular bupivacaine hip injection in differentiation of coxarthrosis from referred thigh pain: a 10 year study. Acta Orthop Belg. 2003;69(6):518–21.

    PubMed  Google Scholar 

  6. Illgen RL, Honkamp NJ, Weisman MH, Hagenauer ME, Heiner JP, Anderson PA. The diagnostic and predictive value of Hip Anaesthetic Arthrograms in selected patients before total hip arthroplasty. J Arthroplasty. 2006;21(5):724–30.

    Article  Google Scholar 

  7. Pateder DB, Hungerford MW. Use of fluoroscopically guided intra-articular hip injection in differentiating the pain source in concomitant hip and lumbar spine arthritis. Am J Orthop. 2007;36(11):591–3.

    PubMed  Google Scholar 

  8. Byrd JWT, Jones KS. Diagnostic accuracy of clinical assessment, magnetic resonance imaging, magnetic resonance arthrography, and intra-articular injection in hip arthroscopy patients. Am J Sports Med. 2004;37(7):1668–74.

    Article  Google Scholar 

  9. Deshmukh AJ, Thakur RR, Goyal A, Klein DA, Ranawat AS, Rodriguez, JA. Accuracy of diagnostic injection in differentiating source of atypical hip pain. J Arthroplasty 2010;25(6 Suppl):129–33.

    Article  Google Scholar 

  10. Jones A, Doherty M. Intra-articular corticosteroids are effective in osteoarthritis but there are no clinical predictors of response. Ann Rheum Dis. 1996;55(11):829–32.

    Article  CAS  Google Scholar 

  11. Robinson P, Keenan A-M, Conaghan PG. Clinical effectiveness and dose response of image-guided intra-articular corticosteroid injection for hip osteoarthritis. Rheumatology. 2007;46:285–91.

    Article  CAS  Google Scholar 

  12. Kullenberg B, Runesson R, Tuvhag R, Olsson C, Resch S. Intraarticular corticosteroid injection: pain relief in osteoarthritis of the hip? J Rheumatol. 2004;31(11):2265–8.

    PubMed  Google Scholar 

  13. Plant MJ, Borg AA, Dziedzic K, Saklatvala J, Dawes PT. Radiographic patterns and response to corticosteroid hip injection. Ann Rheum Dis. 1997;56(8):476–80.

    Article  CAS  Google Scholar 

  14. Kruse DW. Intraarticular cortisone injection for osteoarthritis of the hip. Is it effective? Is it safe? Curr Rev Musculoskelet Med. 2008;1(3-4):227–33.

    Article  Google Scholar 

  15. Lambert RGW, Hutchings EJ, Grace MGA, Jhangri GS, Conner-Spady B, Maksymowych WP. Steroid injection for osteoarthritis of the hip. A randomized, double-blind, placebo-controlled trial. Arthritis Rheum. 2007;56(7):2278–87.

    Article  CAS  Google Scholar 

  16. Kellgren JH, Lawrence JS. Radiological assessment of osteo-arthritis. Ann Rheum Dis. 1957;16:494–502.

    Article  CAS  Google Scholar 

  17. Leveaux VM, Quin CE. Local injections of hydrocortisone and procaine in osteoarthritis of the hip. Ann Rheum Dis. 1956;15:330–7.

    Article  CAS  Google Scholar 

  18. Qvistgaard E, Kristoffersen H, Terslev L, Danneskiold-Samsoe B, Torp-Pedersen S, Bliddal H. Guidance by ultrasound of intraarticular injections in the knee and hip joints. Osteoarthritis Cartilage. 2001;9:512–7.

    Article  CAS  Google Scholar 

  19. Larsen A, Dale K, Eek M. Radiographic evaluation of rheumatoid arthritis and related conditions by the standard reference films. Acta Radiol Diagn. 1977;18:481–491.

    Article  CAS  Google Scholar 

  20. Solomon L. Patterns of osteoarthritis of the hip. J Bone Joint Surg Br. 1976;58:176–83.

    Article  CAS  Google Scholar 

  21. Gaffney K, Ledingham J, Perry JD. Intra-articular triamcinolone hexacetonide in knee osteoarthritis-factors influencing the clinical response. Ann Rheum Dis. 1995;54:379–81.

    Article  CAS  Google Scholar 

  22. Peterson C, Holder J. Evidence based radiology . II. Is there sufficient evidence to support the use of therapeutic injections into the peripheral joints? Skeletal Radiol. 2010;39:11–8.

    Article  Google Scholar 

  23. Chu CR, Izzo NJ, Coyle Ch, Papas NE, Logar A. The in vitro effects of bupivacaine on articular chondrocytes. J Bone Joint Surg Br. 2008;90(6):814–20.

    Article  CAS  Google Scholar 

  24. Piper SL, Kim HT. Comparison of ropivacaine and bupivacaine toxicity in human articular chondrocytes. J Bone Joint Surg Br. 2008;90:986–91.

    Article  Google Scholar 

  25. Chu CR, Coyle CH, Chu CT, Szczodry M, Seshadri V, Karpie JC, et al. In vivo effects on single intra-articular injection of 0.5% bupivacaine on articular cartilage. J Bone Joint Surg Am. 2010;92:599–608.

    Article  Google Scholar 

  26. Kamath R, Strichartz G, Rosenthal D. Cartilage toxicity from local anesthetics. Skeletal Radiol. 2008;37:871–3.

    Article  Google Scholar 

Download references

Acknowledgement

No benefits or funds were received in support of this study.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Ajit J. Deshmukh.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Deshmukh, A.J., Panagopoulos, G., Alizadeh, A. et al. Intra-articular hip injection: does pain relief correlate with radiographic severity of osteoarthritis?. Skeletal Radiol 40, 1449–1454 (2011). https://doi.org/10.1007/s00256-011-1120-8

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00256-011-1120-8

Keywords

Navigation