Original article: general thoracicA clinicopathological study of resected subcentimeter lung cancers: a favorable prognosis for ground glass opacity lesions
Section snippets
Patients
For the 10-year period from January 1991 through December 2000 there were 1,769 pulmonary resections for primary lung cancer including low-grade malignancy at the National Cancer Center Hospital, Tokyo. Among these the diameter of resected primary tumor was 1.0 cm or less in 51 patients (subcentimeter lung cancers). The location of tumor was central in the bronchial lumen in 3 patients and peripheral in the lung parenchyma in 48 patients. The clinicopathological characteristics of these 48
Results
The clinicopathological aspects of 48 subcentimeter cancers were analyzed according to the three types of lesion.
Comment
Owing to the advent of new technology in CT scanning such small-sized lung cancers as those of subcentimeter size are being found in a daily practice. Subcentimeter lung cancers still belong to a rare category of tumor size as lung cancer and most of them are expected to be in an early stage of the disease. In the present series however the lymph node metastasis was seen in 3 (15%) of 48 patients with subcentimeter lung cancer and furthermore 2 of them had recurrence of the tumor. These
Acknowledgements
Supported in part by a Grant-in-Aid for Cancer Research (Grant 11-19) from the Ministry of Health and Welfare, Japan
References (15)
- et al.
Early lung cancer action projectoverall design and findings from baseline screening
Lancet
(1999) - et al.
Mass screening for lung cancer with mobile spiral computed tomography scanner
Lancet
(1998) - et al.
Prognostic significance of the size of central fibrosis in peripheral adenocarcinoma of the lung
Ann Thorac Surg
(2000) - et al.
Randomized trial of lobectomy versus limited resection for T1N0 non-small cell lung cancer
Ann Thorac Surg
(1995) - et al.
Histological typing of lung and pleural tumors, World Health Organization international histological classification of tumors
(1999) Radiologic evaluation of the solitary pulmonary nodule
AJR Am J Roentgenol
(1990)- et al.
High-resolution CT of bronchioloalveolar carcinoma
AJR Am J Roentgenol
(1992)
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Development and validation of a radiomics nomogram for identifying invasiveness of pulmonary adenocarcinomas appearing as subcentimeter ground-glass opacity nodules
2019, European Journal of RadiologyCitation Excerpt :Wu et al. investigated the CT features of subcentimeter pure GGNs (pGGNs) and concluded that vessel changes, unsmooth margin, and clear lung-tumor interface may all indicate the invasiveness of subcentimeter pGGNs [26]; yet, his study included only pGGNs and a small sample size (150 lesions). In clinical context, part-solid GGNs consist of an important proportion of subcentimeter pulmonary adenocarcinomas [7,25]. To comprehensively investigated the characteristics of subcentimeter GGNs, both of pGGNs and part-solid GGNs were included in this study.
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