Original ArticlePresence of Medical Comorbidities in Patients With Infected Primary Hip or Knee Arthroplasties
Section snippets
Method
Ethical approval was obtained from the author's institutional review board. The case group was identified using the senior authors' ongoing prospective arthroplasty database and consisted of patients referred to our academic arthroplasty unit over a 7-year period for management of a deep infection of a primary hip or knee joint arthroplasty. The diagnosis of infection was confirmed by either positive culture by aspiration preoperatively or by tissue sample at time of surgery, or a clinical
Results
Fifty-one patients with 52 joint infections were identified for the case group; 1 patient had suffered infection of both THA and TKA on separate occasions. The case group was composed of 27 males and 24 females with an average age of 62.5 years, 22 patients had undergone THA, and 30 had undergone TKA. Body mass index information was available for 39 of the patients. The indication for primary arthroplasty was osteoarthritis in 31 cases and rheumatoid arthritis in 4 cases, and could not be
Discussion
In this study, the presence of various medical comorbidities by specific disease and body systems among patients with infected prosthetic joints was compared with those without infection. The presence of diabetes raised the odds of developing a joint infection by almost 4-fold (OR, 3.91). The presence of genitourinary conditions was associated with nearly 3 times increased odds of developing a joint infection (OR, 2.73), although statistical significance was not quite reached in the
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2023, Arthroplasty TodayCitation Excerpt :Moreover, according to an estimate, health-care expenditure for revision surgeries will also increase, reaching $1.6 billion in 2020 [6]. Therefore, preventing these infections is becoming more important considering the recently growing number of patients at high risk of infection (eg, elderly patients and those with diabetes mellitus, chronic hepatitis, chronic renal dysfunction, immunosuppression due to collagen disease and malignant neoplasm, and previous hip surgery and infection) [7-9]. Numerous studies have reported using implants with antibacterial activity to prevent infection [10-14].
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No benefits or funds were received in support of the study.