Computer-assisted endoscopic coronary artery bypass anastomoses: a chronic animal study

Ann Thorac Surg. 1999 Sep;68(3):838-43. doi: 10.1016/s0003-4975(99)00794-8.

Abstract

Background: With traditional instruments, endoscopic coronary artery bypass grafting (ECABG) has not been possible. This study was designed to determine the feasibility of using a robotically-assisted microsurgical system to perform ECABG in a chronic animal model.

Methods: Nine calves were placed on cardiopulmonary bypass after harvesting the left internal mammary artery (LIMA). Subxiphoid endoscopic ports (2 instrument, 1 camera) were placed, and a robotic system was used to perform ECABG between the LIMA and left anterior descending coronary artery. LIMA graft flow (LIMAQ) was measured. Animals were sacrificed at 1 month, and hearts underwent angiographic and histologic analyses.

Results: Acute graft patency was 89% (8/9). Two animals died suddenly within the first 48 hours. There was no significant difference in mean acute and chronic (n = 6) LIMAQ (40.9+/-4.7 and 38.5+/-5.0 ml/min, respectively). Survivors had an angiographic patency rate of 100% (6/6), confirmed by histology.

Conclusions: This study shows that ECABG is feasible in a chronic animal model with excellent results.

MeSH terms

  • Anastomosis, Surgical / methods
  • Animals
  • Cattle
  • Coronary Angiography
  • Coronary Artery Bypass / methods*
  • Coronary Circulation
  • Echocardiography
  • Endoscopes
  • Endoscopy / methods*
  • Feasibility Studies
  • Microsurgery / instrumentation
  • Microsurgery / methods
  • Robotics*
  • Therapy, Computer-Assisted
  • Vascular Patency