Successful preoperative treatment of pediatric bladder inflammatory myofibroblastic tumor with anti-inflammatory therapy

Alisa Berger; Christina Kim; Nathan Hagstrom; Fernando Ferrer

doi:10.1016/j.urology.2007.04.047

Successful preoperative treatment of pediatric bladder inflammatory myofibroblastic tumor with anti-inflammatory therapy

Urology. 2007 Aug;70(2):372.e13-5. doi: 10.1016/j.urology.2007.04.047.

Authors

Alisa Berger¹, Christina Kim, Nathan Hagstrom, Fernando Ferrer

Affiliation

¹ Division of Pediatric Urology and University of Connecticut Health Center, Farmington, Connecticut, USA.

PMID: 17826515
DOI: 10.1016/j.urology.2007.04.047

Abstract

Inflammatory myofibroblastic tumors are rare, locally invasive tumors that can involve the genitourinary tract. Therapy has consisted primarily of surgery, and anecdotal experience using both chemotherapy and radiotherapy, which have yielded unimpressive results. We report the first case of a bladder inflammatory myofibroblastic tumor that responded to an anti-inflammatory regimen (prednisone and Cox-2 inhibitor) before surgical extirpation.

Publication types

Case Reports

MeSH terms

Antineoplastic Agents, Hormonal / therapeutic use*
Child, Preschool
Cyclooxygenase 2 Inhibitors / therapeutic use*
Humans
Inflammation / complications
Male
Neoplasms, Muscle Tissue / complications
Neoplasms, Muscle Tissue / drug therapy*
Prednisone / therapeutic use*
Preoperative Care
Remission Induction
Urinary Bladder Neoplasms / complications
Urinary Bladder Neoplasms / drug therapy*

Substances

Antineoplastic Agents, Hormonal
Cyclooxygenase 2 Inhibitors
Prednisone