Duration of off-loading and recurrence rate in Charcot osteo-arthropathy treated with less restrictive regimen with removable walker

J Diabetes Complications. 2012 Sep-Oct;26(5):430-4. doi: 10.1016/j.jdiacomp.2012.05.006. Epub 2012 Jun 12.

Abstract

Objective: Recent literature on acute diabetic Charcot osteoarthropathy (CA) reports unusually long periods of off-loading. Data suggest that this might increase the re-currence rate. Subsequently we evaluated the influence of duration of off-loading on the risk of required re-casting.

Research design and methods: In this retrospective consecutive series from 2000 to 2005, 56 people with diabetes and an acute Charcot foot were included. The inclusion criteria were an initial persistent temperature difference more than 2°C between the two feet, oedema, and typical hot spots on a bone scintigram, radiology, and a typical clinical course. Treatment was off-loading in a removable cast and 2 crutches. In-door walking was allowed. Gradually augmented weight bearing was prescribed when the skin temperature difference had decreased to a level less than 2°C and edema had subsided. Re-casting was required for immediate exacerbation during re-load as well as for recurrence - defined as new swelling and skin temperature difference of more than 2°C in the same foot occurring after a stable interval of at least one month after full weight bearing.

Results: The duration of off-loading for all patients was 141±21 days (mean±SD). Three patients (5%) were re-casted immediately for exacerbation after re-load and 7 patients (12 %) after recurrence of the CA. Duration of re-casting was 79±44 days. The primary period of off-loading was not statistically significantly different for those not requiring versus those requiring re-casting: 142±24 days compared to 134±41 days. Neither were the differences in demographic data, metabolic regulation, BMI or localization of CA.

Conclusions: Patients with risk of exacerbation or recurrence of CA could not be identified in the present study and there was no relation to the duration of off-loading. Nevertheless off-loading periods with immobilisation should be kept as short as possible, due to other side effects. This can be obtained by early gradual augmented re-loading.

MeSH terms

  • Adult
  • Aged
  • Arthropathy, Neurogenic / complications
  • Arthropathy, Neurogenic / physiopathology
  • Arthropathy, Neurogenic / rehabilitation
  • Arthropathy, Neurogenic / therapy*
  • Casts, Surgical
  • Diabetes Mellitus, Type 1 / complications
  • Diabetes Mellitus, Type 2 / complications
  • Diabetic Foot / physiopathology
  • Diabetic Foot / rehabilitation
  • Diabetic Foot / therapy*
  • Diabetic Neuropathies / physiopathology
  • Diabetic Neuropathies / rehabilitation
  • Diabetic Neuropathies / therapy*
  • Exercise Therapy / adverse effects
  • Exercise Therapy / methods*
  • Follow-Up Studies
  • Humans
  • Middle Aged
  • Recurrence
  • Retrospective Studies
  • Severity of Illness Index
  • Time Factors
  • Walkers*
  • Weight-Bearing