Multidimensional measures of caregiver burden give a sensitive reading of caregivers' feelings and a sophisticated picture of caregivers' responses to the demands of care. This paper reports on the development of a 24-item, five-subscale Caregiver Burden Inventory (CBI) and demonstrates its use as a diagnostic tool for professional caregivers. It concludes with a discussion of several ways that professional caregivers can use this multidimensional measure of caregiver burden.