Medial collateral ligament healing. A multidisciplinary assessment in rabbits

Am J Sports Med. 1983 Nov-Dec;11(6):379-89. doi: 10.1177/036354658301100602.

Abstract

Medial collateral ligament healing without treatment has been studied in a rabbit model. Complete midsubstance gaps were found to heal by distinct scar formation over time. This healing process was fast since the gap was bridged quickly; however, more subtle changes in appearance of the healing tissue continued for many months. The ligament "scar" was found to be structurally abnormal chemically and mechanically even at long-term followup. A plateau in its improvement suggests that the scar may never approach normal ligament characteristics (without treatment). A baseline of ligament healing by scar formation has been established.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Biomechanical Phenomena
  • Body Water / analysis
  • Cicatrix / pathology
  • Collagen / analysis
  • DNA / analysis
  • Glycosaminoglycans / analysis
  • Knee Joint*
  • Ligaments, Articular / injuries*
  • Ligaments, Articular / physiopathology
  • Male
  • Rabbits
  • Wound Healing*

Substances

  • Glycosaminoglycans
  • Collagen
  • DNA