The generation of transgenic pigs as potential organ donors for humans

Nat Med. 1995 Sep;1(9):964-6. doi: 10.1038/nm0995-964.
No abstract available

Publication types

  • Review

MeSH terms

  • Animals
  • Animals, Genetically Modified* / blood
  • Animals, Genetically Modified* / genetics
  • Animals, Genetically Modified* / immunology
  • CD55 Antigens / genetics
  • CD55 Antigens / physiology
  • CD59 Antigens / genetics
  • CD59 Antigens / physiology
  • Carbohydrate Sequence
  • Complement Activation*
  • Complement C3-C5 Convertases / metabolism
  • Complement Membrane Attack Complex / metabolism
  • Endothelium, Vascular / physiology
  • Enzyme Activation
  • Epitopes / genetics
  • Epitopes / immunology
  • Forecasting
  • Graft Rejection / physiopathology
  • Graft Rejection / prevention & control*
  • Humans
  • Mice
  • Mice, Transgenic
  • Molecular Sequence Data
  • Swine / blood
  • Swine / genetics*
  • Swine / immunology
  • Tissue Donors*
  • Transplantation, Heterologous* / immunology

Substances

  • CD55 Antigens
  • CD59 Antigens
  • Complement Membrane Attack Complex
  • Epitopes
  • Complement C3-C5 Convertases