Factors affecting survival after excision of the rectum for cancer: a multivariate analysis

Dis Colon Rectum. 1997 Jan;40(1):3-10. doi: 10.1007/BF02055674.

Abstract

Purpose: The aim of this study was to identify and categorize the independent prognostic effects of patient, clinical, operative, and pathology variables on long-term survival after anterior resection or abdominoperineal excision of the rectum for cancer.

Methods: Proportional hazards regression analysis was used to analyze prospective data from 709 patients who underwent surgery at Concord Hospital during a 23-year period. No patient received adjuvant therapy.

Results and conclusions: After adjusting for age and clinicopathologic stage, significantly poorer survival was experienced by males, patients with extensive tumor adherent to other organ(s), those with a high-grade tumor or a tumor showing venous invasion, those who had a postoperative cardiovascular or respiratory complication, and those who did not undergo surgery by a colorectal surgeon specialist. The nature of the operation performed had no independent effect on survival.

MeSH terms

  • Anastomosis, Surgical
  • Female
  • Humans
  • Male
  • Multivariate Analysis
  • Neoplasm Staging
  • Postoperative Complications
  • Prognosis
  • Proportional Hazards Models
  • Prospective Studies
  • Rectal Neoplasms / mortality
  • Rectal Neoplasms / surgery*
  • Rectum / surgery
  • Survival Analysis