This study presents a modification of the medial parapatellar surgical approach for total knee arthroplasty. This approach separates the vastus medialis muscle in the direction of its fibers beginning at the superior pole of the patella. One hundred eighteen consecutive total knee arthroplasty cases, performed by a single surgeon, were randomized prospectively to receive a medial parapatellar or midvastus muscle-splitting surgical approach. The frequency of lateral retinacular releases was recorded, patellar tilt and translation were measured, and quadriceps strength was tested. The midvastus muscle-splitting approach provided excellent exposure to all knees. Patellar stability and quadriceps strength were equivalent for the two approaches. It is concluded that the midvastus muscle-splitting approach is an efficacious alternative to the medial parapatellar approach for primary total knee arthroplasties.