User profiles for A. Arnaout

MA Arnaout

- Verified email at mgh.harvard.edu - Cited by 26481

Adnan Arnaout

- Verified email at prevailtherapeutics.com - Cited by 430

Carbon nanotubes in biomedical applications: factors, mechanisms, and remedies of toxicity: miniperspective

R Alshehri, AM Ilyas, A Hasan, A Arnaout… - Journal of medicinal …, 2016 - ACS Publications
Carbon nanotubes (CNTs) represent one of the most studied allotropes of carbon. The unique
physicochemical properties of CNTs make them among prime candidates for numerous …

MRI for detection of extramural vascular invasion in rectal cancer

NJ Smith, O Shihab, A Arnaout… - American Journal of …, 2008 - Am Roentgen Ray Soc
OBJECTIVE. Extramural vascular invasion is a pathologic feature predictive of distant relapse
and poor survival among patients with colorectal cancer. This article illustrates the use of …

Sentinel node biopsy after neoadjuvant chemotherapy in biopsy-proven node-positive breast cancer: the SN FNAC study

…, L Sideris, S Meterissian, A Arnaout… - Journal of Clinical …, 2015 - ascopubs.org
Purpose An increasing proportion of patients (> 30%) with node-positive breast cancer will
obtain an axillary pathologic complete response after neoadjuvant chemotherapy (NAC). If …

Sites of distant recurrence and clinical outcomes in patients with metastatic triple‐negative breast cancer: high incidence of central nervous system metastases

NU Lin, E Claus, J Sohl, AR Razzak, A Arnaout… - Cancer, 2008 - Wiley Online Library
BACKGROUND. The purpose of the current study was to characterize the outcomes of
patients with metastatic triple‐negative breast cancers, including the risk and clinical …

[PDF][PDF] Structure and function of the leukocyte adhesion molecules CD11/CD18

MA Arnaout - 1990 - Citeseer
INCE THE EARLY studies of Metchnikoff in the S 1880s,’a large body of data has been
accumulated that established a crucial role for circulating polymorphonuclear leukocytes (PMN) …

[HTML][HTML] p27 phosphorylation by Src regulates inhibition of cyclin E-Cdk2

I Chu, J Sun, A Arnaout, H Kahn, W Hanna, S Narod… - Cell, 2007 - cell.com
The kinase inhibitor p27 Kip1 regulates the G 1 cell cycle phase. Here, we present data
indicating that the oncogenic kinase Src regulates p27 stability through phosphorylation of p27 …

Vegf-a, vegf-c, and vegf-d in colorectal cancer progression

ML George, MG Tutton, F Janssen, A Arnaout… - Neoplasia, 2001 - Elsevier
We aimed to assess the relationship of the angiogenic cytokines VEGF-A, VEGF-C, and
VEGF-D and their receptors VEGFR-2 and VEGFR-3 in the adenomacarcinoma sequence and …

Clinical outcomes and treatment practice patterns of patients with HER2-positive metastatic breast cancer in the post-trastuzumab era

EM Olson, JS Najita, J Sohl, A Arnaout, HJ Burstein… - The Breast, 2013 - Elsevier
BACKGROUND: Trastuzumab is associated with improvements in overall survival (OS)
among patients with HER2-positive metastatic breast cancer (MBC); however disease course …

Accuracy of multidetector computed tomography in identifying poor prognostic factors in colonic cancer

…, H Blake, MD Koh, I Swift, A Arnaout… - Journal of British …, 2010 - academic.oup.com
Background Recent neoadjuvant strategies for high-risk colonic tumours have renewed
interest in accurate preoperative staging. The aim of this study was to validate prospectively the …

Crystal structure of the extracellular segment of integrin αVβ3 in complex with an Arg-Gly-Asp ligand

…, A Joachimiak, M Frech, SL Goodman, MA Arnaout - Science, 2002 - science.org
The structural basis for the divalent cation–dependent binding of heterodimeric αβ integrins
to their ligands, which contain the prototypical Arg-Gly-Asp sequence, is unknown. …