Discussion GISTs display a wide variety of malignant behaviours, and none of these
tumours can be considered completely benign. A National Institutes of Health consensus …

Discussion GISTs are a group of rare tumours of the digestive tract that constitute about 1%
of all gastrointestinal cancers. 1 The incidence of these tumours is about 1–2/100 000, and …

A fit and healthy 47-year-old male presented with abdominal distension, an altered bowel
habit and a palpable epigastric mass on examination. Outpatient computed tomography …

In Reply: We appreciate the comments by Date and Mughal. However, we feel that they
have misinterpreted our editorial on the potential for individualized therapy for …

Discussion Some clinical features in patients who have gastric stromal tumours may suggest
malignancy. In the review by Davis and associates, 2 most malignant tumours (64%) were …

This Annals of Surgical Oncology issue includes a retrospective study evaluating the role of
neodjuvant therapy and different surgical approaches in the management of anorectal …

© 2009 American Medical Association. All rights reserved.(REPRINTED WITH
CORRECTIONS) vorable clinical course than small intestinal GISTs after resection. In a …

Biopsies of the vaginal mass revealed a high-grade spindle cell GIST with a mitotic rate of
30 mitosis per 5 mm2. The immunohistochemical panel revealed a positive staining for …

Gastrointestinal stromal tumors (GISTs) are mesenchymal tumors that are thought to be
derived from the interstitial cells of Cajal within the gastrointestinal tract. 1, 2 GISTs can …

Gastrointestinal stromal tumors (GISTs) are infrequent but are the most common
mesenchymal neoplasm of the gastrointestinal tract. 1 GISTs are mainly diagnosed in adults …